Evidence map›Paper›PMID 35576492›Full record

ArticleThe American surgeon2022

Thromboelastography-Based Evaluation of Gender-Associated Hypercoagulability.

Skylar C Rodgers, Kristen T Carter, Deepti Patki, Robert C O'Brien, Matthew E Kutcher

Open access · greenAbstract read
In one paragraph

Article in The American surgeon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Liquid Trisilanol i-Octyl POSS Achieves Rapid Hemostasis and Pneumostasis in Experimental Lung Injury.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025
    Article
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  7. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Skylar C RodgersDepartment of Surgery, 8083University of Mississippi Medical Center, Jackson, MS, USA.
Kristen T CarterDepartment of Surgery, 8083University of Mississippi Medical Center, Jackson, MS, USA.
Deepti PatkiDepartment of Surgery, 8083University of Mississippi Medical Center, Jackson, MS, USA.
Robert C O'BrienDepartment of Surgery, 8083University of Mississippi Medical Center, Jackson, MS, USA.
Matthew E KutcherDepartment of Surgery, 8083University of Mississippi Medical Center, Jackson, MS, USA.
Jackson Memorial Hospital · USUniversity of Mississippi Medical Center · US

Funding

Tracking and Evaluation CoreU54GM115428 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI COMPRETTA, CAROLINE E. · 2016 to 2025
$38.2M
Hypertension and Cardiorenal Research Training ProgramT32HL105324 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI Joey P. Granger · 2010 to 2026
$7.8M
Mitochondrial DNA in the pathogenesis of post-injury coagulopathyK08GM138812 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI KUTCHER, MATTHEW E · 2020 to 2024
$787k
NHLBI NIH HHS T32 HL105324NIGMS NIH HHS K08 GM138812NIGMS NIH HHS U54 GM115428
6 · The paper itself

Abstract

backgroundAge, race, and gender differences in coagulation status of healthy volunteers have been reported in previous case series; however, rigorous multivariate analysis adjusting for these factors is lacking. We aimed to investigate the effects of age, race, and gender on baseline coagulation status in healthy volunteers.

methodsThirty healthy volunteer controls with no history of bleeding or thrombotic events and no previous anticoagulant or antiplatelet use were recruited. Citrated and heparinized blood samples were drawn, and kaolin and platelet-mapping thromboelastography (TEG) assays performed.

resultsThirty participants had a mean age of 37, mean body mass index of 29 kg/m DISCUSSION: Women at baseline have relatively hypercoagulable fibrin deposition kinetics, platelet contributions to clot formation, and overall clot strength compared to men, even when adjusted for age and race. Additional research is needed to specifically detail the key patient-level factors, clinical implications, and opportunities for tailored therapy related to gender-associated hypercoagulability.

Indexed as

ThrombophiliaThrombosisAdultAnticoagulantsFemaleFibrinHumansKaolinMaleThrombelastographyAnticoagulantsFibrinKaolingender dimorphismhypercoagulabilitythromboelastography

Identifiers

PMID35576492
PMCPMC9588506
OpenAlexW4280498136

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.