ArticlePlant communications2022
Horizontal transfer and evolution of the biosynthetic gene cluster for benzoxazinoids in plants.
Article in Plant communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22 citing papers in PubMed, 34 citations in OpenAlex.
- Evolutionary divergence and regulatory landscapes of benzoxazinoid metabolism in monocot crops.Plant cell reports · 2026Review
- Biosynthesis of pathogen-induced hydroxylated tryptamine derivatives in barley.Plant physiology · 2026Article
- Evolutionary tuning of a biosynthetic gene cluster drives furanocoumarin accumulation and diversification.Nature communications · 2026Article
- Comparative genomics reveals the evolution of anthraquinone biosynthesis in Polygonaceae.BMC genomics · 2026Article
- RIFinder reveals widespread adaptive remote introgression in grass genomes.Plant communications · 2026Article
- A pseudoenzyme enables indole biosynthesis in eudicot plants.Nature chemical biology · 2026Article
- Metabolite-based resistance in wheat varieties to aphid virus vectors: progress and future opportunities.Pest management science · 2025Review
- Metabolomic Analysis Reveals the Diversity of Defense Metabolites in Nine Cereal Crops.Plants (Basel, Switzerland) · 2025Article
- Understanding metabolic diversification in plants: branchpoints in the evolution of specialized metabolism.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- The gradual establishment of complex coumarin biosynthetic pathway in Apiaceae.Nature communications · 2024Article
- Benzoxazinoids Biosynthetic Gene Cluster Identification and Expression Analysis in Maize under Biotic and Abiotic Stresses.International journal of molecular sciences · 2024Article
- Genome-wide identification and analysis of monocot-specific chimeric jacalins (MCJ) genes in Maize (Zea mays L.).BMC plant biology · 2024Article
- Variation in leaf dark respiration among C3 and C4 grasses is associated with use of different substrates.Plant physiology · 2024Article
- Genome-Wide Identification and Expression Analysis ofPlants (Basel, Switzerland) · 2024Article
- Mechanism of benzoxazinoids affecting the growth and development of Fusarium oxysporum f. sp. fabae.Plant molecular biology · 2024Article
- Weed biology and management in the multi-omics era: Progress and perspectives.Plant communications · 2024Review
- The evolutionary trajectories of specialized metabolites towards antiviral defense system in plants.Molecular horticulture · 2024Review
- Weed genomics: yielding insights into the genetics of weedy traits for crop improvement.aBIOTECH · 2023Review
- Unraveling the evolutionary dynamics of theFrontiers in plant science · 2023Article
- Functional diversity and metabolic engineering of plant-specialized metabolites.Life metabolism · 2022Review
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Benzoxazinoids are a class of protective and allelopathic plant secondary metabolites that have been identified in multiple grass species and are encoded by the Bx biosynthetic gene cluster (BGC) in maize. Data mining of 41 high-quality grass genomes identified complete Bx clusters (containing genes Bx1-Bx5 and Bx8) in three genera (Zea, Echinochloa, and Dichanthelium) of Panicoideae and partial clusters in Triticeae. The Bx cluster probably originated from gene duplication and chromosomal translocation of native homologs of Bx genes. An ancient Bx cluster that included additional Bx genes (e.g., Bx6) is presumed to have been present in ancestral Panicoideae. The ancient Bx cluster was putatively gained by the Triticeae ancestor via horizontal transfer (HT) from the ancestral Panicoideae and later separated into multiple segments on different chromosomes. Bx6 appears to have been under less constrained selection compared with the Bx cluster during the evolution of Panicoideae, as evidenced by the fact that it was translocated away from the Bx cluster in Zea mays, moved to other chromosomes in Echinochloa, and even lost in Dichanthelium. Further investigations indicate that purifying selection and polyploidization have shaped the evolutionary trajectory of Bx clusters in the grass family. This study provides the first candidate case of HT of a BGC between plants and sheds new light on the evolution of BGCs.
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