Evidence map›Paper›PMID 35576080›Full record

ReviewDiscover oncology2022

Cancer vaccines: past, present and future; a review article.

Eddie Grimmett, Bayan Al-Share, Mohamad Basem Alkassab, Ryan Weng Zhou, Advait Desai, Mir Munir A Rahim, Indryas Woldie

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Discover oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 62 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Eddie GrimmettDepartment of Biomedical Sciences, University of Windsor, Windsor, ON, Canada.
Bayan Al-ShareBarbara Ann Karmanos Cancer Institute, Detroit, MI, USA.
Mohamad Basem AlkassabDepartment of Biomedical Sciences, University of Windsor, Windsor, ON, Canada.
Ryan Weng ZhouDepartment of Biomedical Sciences, University of Windsor, Windsor, ON, Canada.
Advait DesaiDepartment of Biomedical Sciences, University of Windsor, Windsor, ON, Canada.
Mir Munir A RahimDepartment of Biomedical Sciences, University of Windsor, Windsor, ON, Canada. munir.rahim@uwindsor.ca.
Indryas WoldieDepartment of Biomedical Sciences, University of Windsor, Windsor, ON, Canada. indryas.woldie@wrh.on.ca.
University of Windsor · CAThe Barbara Ann Karmanos Cancer Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapy and vaccines have revolutionized disease treatment and prevention. Vaccines against infectious diseases have been in use for several decades. In contrast, only few cancer vaccines have been approved for human use. These include preventative vaccines against infectious agents associated with cancers, and therapeutic vaccines used as immunotherapy agents to treat cancers. Challenges in developing cancer vaccines include heterogeneity within and between cancer types, screening and identification of appropriate tumour-specific antigens, and the choice of vaccine delivery platforms. Recent advances in all of these areas and the lessons learnt from COVID-19 vaccines have significantly boosted interest in cancer vaccines. Further advances in these areas are expected to facilitate development of effective novel cancer vaccines. In this review, we aim to discuss the past, the present, and the future of cancer vaccines.

Identifiers

PMID35576080
PMCPMC9108694
OpenAlexW4280524562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.