Expression of microRNA-223 and microRNA-146b in serum and liver tissue of mice infected with Schistosoma mansoni.

Hend A El-Taweel, Yasmine A Issa, Rasha F Mady, Ghada A Shehata, Eman A Youssef, Mona M Tolba

Open access · hybridAbstract read

In one paragraph

Article in Parasitology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

1.1field-weighted citation impact, top 29% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

Unveiling the hemolymphatic miRNome composition of the schistosomiasis vector snailCurrent research in parasitology & vector-borne diseases · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hend A El-TaweelDepartment of Parasitology, Medical Research Institute, Alexandria University, Alexandria, Egypt. hend.eltaweel@alexu.edu.eg.ORCID http://orcid.org/0000-0001-5152-2704

Yasmine A IssaDepartment of Medical Biochemistry, Alexandria University, Alexandria, Egypt.

Rasha F MadyDepartment of Medical Parasitology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.

Ghada A ShehataDepartment of Parasitology, Medical Research Institute, Alexandria University, Alexandria, Egypt.

Eman A YoussefDepartment of Histochemistry and Cell Biology, Medical Research Institute, Alexandria University, Alexandria, Egypt.

Mona M TolbaDepartment of Parasitology, Medical Research Institute, Alexandria University, Alexandria, Egypt.

Alexandria University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) play regulatory roles in several diseases. In schistosomiasis, the main pathological changes are caused by the granulomatous reaction induced by egg deposition. We aimed to study the changes in host miRNA-223 and miRNA-146b expression in relation to egg deposition and development of hepatic pathology in murine schistosomiasis mansoni. Blood and liver tissue samples were collected from non-infected mice (group I), S. mansoni-infected mice at the 4th, 8th, and 12th weeks post-infection (p.i.) (groups II-IV), and 4 weeks after praziquantel treatment (group V). The collected samples were processed for RNA extraction, reverse transcription, and real-time PCR analysis of miRNA-223 and miRNA-146b. miRNAs' relative expression was estimated by the ΔΔC

Indexed as

MicroRNAsSchistosomiasisSchistosomiasis mansoniAnimalsLiverMiceSchistosoma mansoniMicroRNAsMIRN223 microRNA, mouseGranulomasLiver fibrosismiRNA-146bmiRNA-223PraziquantelSchistosoma mansoni

Identifiers

PMID35576078

DOI10.1007/s00436-022-07542-3

PMCPMC9192441

OpenAlexW4280559593

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.