Evidence map›Paper›PMID 35575827›Full record

ArticleBrain structure & function2022

Lesion network mapping of mania using different normative connectomes.

Gonçalo Cotovio, Francisco Faro Viana, Michael D Fox, Albino J Oliveira-Maia

Open access · hybridAbstract read
In one paragraph

Article in Brain structure & function, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Gonçalo CotovioChampalimaud Research and Clinical Centre, Champalimaud Foundation, Lisbon, Portugal.
Francisco Faro VianaChampalimaud Research and Clinical Centre, Champalimaud Foundation, Lisbon, Portugal.
Michael D FoxCenter for Brain Circuit Therapeutics, Departments of Neurology, Psychiatry, and Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Albino J Oliveira-MaiaChampalimaud Research and Clinical Centre, Champalimaud Foundation, Lisbon, Portugal. albino.maia@neuro.fchampalimaud.org.ORCID http://orcid.org/0000-0001-5071-3007
Champalimaud Foundation · PTBrigham and Women's Hospital · US

Funding

Using human brain connectivity to identify the causal neuroanatomical substrate of depression symptomsR01MH113929 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI MICHAEL D FOX · 2017 to 2026
$6.9M
Repetitive TMS-induced modulation of cortical excitability in ADR01MH115949 · NIMH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SHAFI, MOUHSIN · 2018 to 2022
$3.2M
Treating hyperexcitability in Alzheimer’s disease with levetiracetam to improve brain function and cognitionR01AG060987 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SHAFI, MOUHSIN · 2019 to 2023
$3.0M
Fundação para a Ciência e a Tecnologia FCT-PTDC/MEC-PSQ/30302/2017-IC&DT-LISBOA-01-0145-FEDERFundação para a Ciência e a Tecnologia FCT-PTDC/MED-NEU/31331/2017Fundação para a Ciência e a Tecnologia SFRH/BD/130210/2017NIA NIH HHS R01 AG060987NIMH NIH HHS R01 MH113929NIMH NIH HHS R01 MH115949
6 · The paper itself

Abstract

Lesion network mapping is a neuroimaging technique that explores the network of regions functionally connected to lesions causing a common syndrome. The technique uses resting state functional connectivity from large databases of healthy individuals, i.e., connectomes, and has allowed for important insight into the potential network mechanisms underlying several neuropsychiatric disorders. However, concerns regarding reproducibility have arisen, that may be due to the use of different connectomes, with variable MRI acquisition parameters and preprocessing methods. Here, we tested the impact of using different connectomes on the results of lesion network mapping for mania. We found results were reliable and consistent independent of the connectome used.

Indexed as

ConnectomeBrainHumansMagnetic Resonance ImagingManiaReproducibility of ResultsConnectomeLesion network mappingManiaReproducibility

Identifiers

PMID35575827
PMCPMC9653320
OpenAlexW4280508587

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.