Evidence map›Paper›PMID 35575577›Full record

ArticleAntimicrobial agents and chemotherapy2022

The NaHCO

Selvi C Ersoy, Adhar C Manna, Richard A Proctor, Henry F Chambers, Ewan M Harrison, Arnold S Bayer, Ambrose Cheung

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Genomic investigation and clinical correlates of theAntimicrobial agents and chemotherapy · 2024
    Trial
  2. An Achilles' heel for methicillin-resistantAntimicrobial agents and chemotherapy · 2026
    Review
  3. Article
  4. Review
  5. International journal of molecular sciences · 2024
    Article
  6. Article
  7. Sensitizing methicillin-resistantAntimicrobial agents and chemotherapy · 2024
    Article
  8. Role of the NaHCOMicrobiology spectrum · 2023
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Selvi C Ersoy *The Lundquist Institute, Torrance, California, USA.ORCID 0000-0002-8792-2061
Adhar C Manna *Department of Microbiology & Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.ORCID 0000-0002-4055-2489
Richard A ProctorUniversity of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Henry F ChambersUCSF School of Medicine, San Francisco, California, USA.
Ewan M HarrisonWellcome Sanger Institute, Hinxton, United Kingdom.
Arnold S Bayer *The Lundquist Institute, Torrance, California, USA.
Ambrose Cheung *Department of Microbiology & Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Dartmouth College · USUniversity of California, Los Angeles · USUniversity of Cambridge · GBUniversity of Wisconsin–Madison · US

Funding

Bicarbonate-Mediated Enhancement of Beta-Lactam-MRSA Killing: Mechanisms and Clinical TranslatabilityR01AI146078 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI XIONG, YAN Q. · 2019 to 2023
$1.9M
HHS | National Institutes of Health (NIH) 5R01AI146078Medical Research Council MR/S00291X/1NIAID NIH HHS R01 AI146078
6 · The paper itself

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) strains are a leading cause of many invasive clinical syndromes, and pose treatment difficulties due to their

Indexed as

Methicillin-Resistant Staphylococcus aureusAnti-Bacterial AgentsBacterial Proteinsbeta-LactamsGenotypeMicrobial Sensitivity TestsOxacillinPenicillin-Binding ProteinsPhenotypeSodium BicarbonateAnti-Bacterial AgentsBacterial Proteinsbeta-LactamsOxacillinPenicillin-Binding ProteinsSodium BicarbonatemecAMethicillin-resistant Staphylococcus aureus (MRSA)penicillin-binding protein 2a (PBP2a)sodium bicarbonate (NaHCO3)β-lactam

Identifiers

PMID35575577
PMCPMC9211399
OpenAlexW4280502362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.