Evidence map›Paper›PMID 35575438›Full record

ArticleHuman brain mapping2022

Multimodal magnetic resonance neuroimaging measures characteristic of early cART-treated pediatric HIV: A feature selection approach.

Isaac L Khobo, Marcin Jankiewicz, Martha J Holmes, Francesca Little, Mark F Cotton, Barbara Laughton, Andre J W van der Kouwe, Allison Moreau, Emmanuel Nwosu, Ernesta M Meintjes and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Human brain mapping, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Isaac L KhoboDivision of Biomedical Engineering, Department of Human Biology, Biomedical Engineering Research Center, University of Cape Town, Cape Town, South Africa.ORCID 0000-0003-2112-1656
Marcin JankiewiczDivision of Biomedical Engineering, Department of Human Biology, Biomedical Engineering Research Center, University of Cape Town, Cape Town, South Africa.
Martha J HolmesDivision of Biomedical Engineering, Department of Human Biology, Biomedical Engineering Research Center, University of Cape Town, Cape Town, South Africa.
Francesca LittleDepartment of Statistical Sciences, University of Cape Town, Cape Town, South Africa.
Mark F CottonDepartment of Pediatrics & Child Health, Family Center for Research with Ubuntu, Tygerberg Hospital, Stellenbosch University, Cape Town, South Africa.
Barbara LaughtonDepartment of Pediatrics & Child Health, Family Center for Research with Ubuntu, Tygerberg Hospital, Stellenbosch University, Cape Town, South Africa.
Andre J W van der KouweDivision of Biomedical Engineering, Department of Human Biology, Biomedical Engineering Research Center, University of Cape Town, Cape Town, South Africa.
Allison MoreauWashington University in St. Louis, St. Louis, Missouri, USA.
Emmanuel NwosuDivision of Biomedical Engineering, Department of Human Biology, Biomedical Engineering Research Center, University of Cape Town, Cape Town, South Africa.
Ernesta M MeintjesDivision of Biomedical Engineering, Department of Human Biology, Biomedical Engineering Research Center, University of Cape Town, Cape Town, South Africa.
Frances C RobertsonDivision of Biomedical Engineering, Department of Human Biology, Biomedical Engineering Research Center, University of Cape Town, Cape Town, South Africa.

Funding

Longitudinal Neuroimaging and Cognitive Study of HIV-Infected ChildrenR01HD071664 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI LAUGHTON, BARBARA, MEINTJES, ERNESTA MARIA · 2011 to 2015
$2.4M
NICHD NIH HHS R01 HD071664NIH HHS R01-HD071664
6 · The paper itself

Abstract

Children with perinatally acquired HIV (CPHIV) have poor cognitive outcomes despite early combination antiretroviral therapy (cART). While CPHIV-related brain alterations can be investigated separately using proton magnetic resonance spectroscopy (

Indexed as

Diffusion Tensor ImagingHIV InfectionsBrainChildHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyNeuroimagingclassificationDTIelastic netHIVMRIMR spectroscopyneuroimagingpediatricregularizationsMRI

Identifiers

PMID35575438
PMCPMC9374890

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.