ArticleInteractive cardiovascular and thoracic surgery2022
Associated factors and short-term mortality of early versus late acute kidney injury following on-pump cardiac surgery.
Article in Interactive cardiovascular and thoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 8 citations in OpenAlex.
- Timing of acute kidney injury in infarction-related cardiogenic shock: early onset signals a high-risk phenotype - a retrospective observational study.BMC nephrology · 2026Observational
- Impact of prognostic scores on acute kidney injury assessment in the postoperative period of myocardial revascularization.Revista da Escola de Enfermagem da U S P · 2025Article
- The incidence, risk factors, and prognosis of acute kidney injury in patients after cardiac surgery.Frontiers in cardiovascular medicine · 2024Article
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Authors and funding
6 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectivesAcute kidney injury (AKI) is common following cardiac surgery. The aim was to investigate the characteristics of AKI that occurred within 48 h and during 48 h to 7 days after cardiac surgery.
methodsPatient data were extracted from Medical Information Mart for Intensive Care III database. AKI was defined according to the Kidney Disease Improving Global Outcomes guideline and divided into early (within 48 h) and late (during 48 h to 7 days) AKI. Multivariable logistic regression models were established to investigate risk factors for AKI. Cox proportional hazards model was used to analyse 90-day survival.
resultsAKI occurred in 51.2% (2741/5356) patients within the first 7 days following cardiac surgery, with the peak occurrence at 36-48 h. The incidence of early and late AKI was 41.9% and 9.2%, respectively. Patients with late AKI were older and had more comorbidities compared to early AKI patients. Risk factors associated with early AKI included age, body mass index, congestive heart failure and diabetes. While late AKI was related to atrial fibrillation, estimated glomerular filtration rate, sepsis, norepinephrine, mechanical ventilation and packed red blood cell transfusion. In Cox proportional model, both late and early AKIs were independently associated with 90-day mortality, and patients with early AKI had better survival than those with late AKI.
conclusionsAKI that occurred earlier was distinguishable from AKI that occurred later after cardiac surgery. Time frame should be taken into consideration.
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