Evidence map›Paper›PMID 35575215›Full record

ArticlePerspectives in public health2023

The changing vaccine landscape: rates of COVID-19 vaccine acceptance and hesitancy in young adults during vaccine rollout.

H Knight, R Jia, K Ayling, H Blake, J R Morling, A M Villalon, J Corner, C Denning, J Ball, K Bolton and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Perspectives in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

H KnightSchool of Medicine, University of Nottingham, Nottingham NG7 2RD, UK.ORCID 0000-0002-4602-3238
R JiaSchool of Medicine, University of Nottingham, Nottingham, UK.
K AylingSchool of Medicine, University of Nottingham, UK.ORCID 0000-0003-1766-8800
H BlakeSchool of Health Sciences, University of Nottingham, Nottingham, UK; NIHR Nottingham Biomedical Research Centre, Nottingham, UK.
J R MorlingSchool of Medicine, University of Nottingham, Nottingham, UK; NIHR Nottingham Biomedical Research Centre, Nottingham, UK.
A M VillalonFaculty of Engineering, University of Nottingham, Nottingham, UK.
J CornerUniversity Executive Board, University of Nottingham, Nottingham, UK.
C DenningBiodiscovery Institute, University Park, University of Nottingham, Nottingham, UK.
J BallBiodiscovery Institute, University Park, University of Nottingham, Nottingham, UK.
K BoltonSchool of Mathematical Sciences, University of Nottingham, Nottingham, UK.
G FigueredoSchool of Computer Sciences, University of Nottingham, Nottingham, UK.
D MorrisFaculty of Engineering, University of Nottingham, Nottingham, UK.ORCID 0000-0001-9813-0767
P TigheSchool of Life Sciences, University of Nottingham, Nottingham, UK.
K VedharaSchool of Medicine, University of Nottingham, Nottingham, UK.ORCID 0000-0002-9940-7534
University of Nottingham · GB

Funding

British Heart Foundation PG/14/59/31000British Heart Foundation PG/21/10545British Heart Foundation SP/15/9/31605Medical Research Council MC_PC_20027Medical Research Council MR/L012618/1Medical Research Council MR/P008348/1
6 · The paper itself

Abstract

aimsDevelopment and rollout of vaccines offers the best opportunity for population protection against the SARS-CoV-2 (COVID-19) virus. However, hesitancy towards the vaccines might impede successful uptake in the United Kingdom, particularly in young adults who demonstrate the highest rates of hesitancy. This prospective study explored COVID-19 vaccine hesitancy in young adults and whether the reasons behind these attitudes changed during the initial stages of the United Kingdom's vaccine rollout.

methodData on vaccination intention were collected from a British university student cohort at three time points: October 2020, February 2021, and March 2021. This online survey included items on intention to receive a vaccine and a free-text response for the reasons behind this intention. Cochran's Q tests examined changes in rates of hesitancy and acceptance over time and free-text responses were analysed thematically.

resultsAt baseline, 893 students provided data, with 476 participants completing all three time points. Hesitancy declined over time, with 29.4% of participants expressing hesitancy at baseline, reducing to 9.1% at wave 2 and 5.9% at wave 3. The most commonly endorsed themes for those willing to accept a vaccine were self-protection against COVID-19 and pro-social reasons, including protecting the population or unspecific others, and ending the pandemic/returning to normal life. The most commonly endorsed hesitancy themes related to 'confidence' in the vaccines and potential personal risk, including insufficient testing/scientific evidence, concern about side effects, and long-term effects. These reasons remained the most commonly endorsed at both waves 2 and 3.

conclusionsWhile a decline in hesitancy was observed over time, the key reasons behind both vaccine acceptance and hesitancy remained consistent. Reasons behind hesitancy aligned with those of the general public, providing support for the use of generalist interventions. Pro-social reasons frequently underpinned vaccine acceptance, so cohort-specific interventions targeting those factors may be of benefit.

Indexed as

COVID-19VaccinesCOVID-19 VaccinesHumansProspective StudiesSARS-CoV-2Young AdultCOVID-19 VaccinesVaccinesCOVID-19public healthvaccine hesitancy

Identifiers

PMID35575215
PMCPMC10467000
OpenAlexW4280603437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.