Evidence map›Paper›PMID 35575196›Full record

ArticleThe Journal of clinical endocrinology and metabolism2022

Role of Weekday Variation on Glucose, Insulin, and Triglyceride: A Cross-Sectional Analysis From the Maastricht Study.

Kim K B Clemmensen, Annemarie Koster, Yannick T H Nielen, Pieter C Dagnelie, Coen D A Stehouwer, Hans Bosma, Anke Wesselius, Kristine Færch, Simone J P M Eussen

Open access · hybridAbstract read
In one paragraph

Article in The Journal of clinical endocrinology and metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Kim K B ClemmensenSteno Diabetes Center Copenhagen, Gentofte, Denmark.
Annemarie KosterDepartment of Social Medicine, Maastricht University, Maastricht, The Netherlands.
Yannick T H NielenDepartment of Clinical Pharmacy and Toxicology, Maastricht University Medical Center+, Maastricht, The Netherlands.
Pieter C DagnelieSchool for Cardiovascular Diseases (CARIM), Maastricht University, Maastricht, The Netherlands.
Coen D A StehouwerSchool for Cardiovascular Diseases (CARIM), Maastricht University, Maastricht, The Netherlands.
Hans BosmaDepartment of Social Medicine, Maastricht University, Maastricht, The Netherlands.
Anke WesseliusDepartment of Complex Genetics and Epidemiology, School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, The Netherlands.
Kristine FærchSteno Diabetes Center Copenhagen, Gentofte, Denmark.ORCID 0000-0002-6127-0448
Simone J P M EussenSchool for Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, The Netherlands.ORCID 0000-0003-0559-6838
Maastricht University · NLMaastricht University Medical Centre · NLSteno Diabetes Centers · DKUniversity of Copenhagen · DK

Funding

Care and Public Health Research InstituteDutch Ministry of Economic Affairs 31O.041European Regional Development FundHealth Foundation LimburgNovo NordiskStichting De Weijerhorst
6 · The paper itself

Abstract

contextThe timing of sleep, physical activity, and dietary intake show variation over the week, with different timings in the weekend compared to the weekdays, which may potentially lead to impaired glucose and lipid regulation on Mondays compared to other weekdays.

objectiveThe aim of the study was to investigate differences in glucose metabolism and fasting triglyceride concentrations on Mondays compared to the rest of the week. DESIGN, SETTING AND

participantsThis cross-sectional study is based on data from the Maastricht Study, including 6067 participants without known diabetes and 1568 previously diagnosed with type 2 diabetes.

main outcome measuresConfounder-adjusted linear regression analysis was applied to study the associations of day of the week of examination with glucose and insulin responses to an oral glucose tolerance test and fasting triglyceride concentrations.

resultsIn fully confounder-adjusted models, mean (95% CI) concentrations of fasting glucose, insulin, and triglycerides were slightly higher on Mondays compared with the other weekdays [glucose: 1% (0-2); insulin: 9% (1-18); triglycerides: 5% (2-8)]. Interaction analyses revealed that the association of weekday with insulin was only pronounced in men [18% (3-35)], but not in women [1% (-8-10)], whereas the associations with glucose and triglycerides were only apparent for individuals with known type 2 diabetes [glucose: 4% (0-7); triglycerides: 14% (6-23)] compared to the background population [glucose: 0% (0-1); triglycerides: 3% (0-6)]. DISCUSSION: Being examined on a Monday was associated with higher fasting insulin concentrations among men but not women.

Indexed as

Diabetes Mellitus, Type 2HyperinsulinismBlood GlucoseCross-Sectional StudiesFastingGlucoseHumansInsulinMaleTriglyceridesBlood GlucoseGlucoseInsulinTriglyceridesmetabolismoral glucose tolerance testtriglycerideweekday

Identifiers

PMID35575196
PMCPMC9797041
OpenAlexW4280501150

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.