Evidence map›Paper›PMID 35575001›Full record

ArticleEquine veterinary journal2023

Noninvasive diode laser-an effective and safe treatment of iris cysts in 46 eyes of 35 horses.

Emanuël K L Stas, Hanneke Hermans, Inge J M Slenter, Stefanie Veraa, Jos M Ensink

Open access · hybridAbstract read
In one paragraph

Article in Equine veterinary journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. A retrospective survey of equine ocular diseases evaluated at a referral hospital in Ontario (2011 to 2021).The Canadian veterinary journal = La revue veterinaire canadienne · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Emanuël K L StasFaculty of Veterinary Medicine, Department Clinical Sciences, Equine Sciences, Equine Surgery and Orthopaedics, Utrecht University, CM, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-6915-9402
Hanneke HermansFaculty of Veterinary Medicine, Department Clinical Sciences, Equine Sciences, Equine Surgery and Orthopaedics, Utrecht University, CM, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-7581-6683
Inge J M SlenterFaculty of Veterinary Medicine, Department Clinical Sciences, Surgery of Companion Animals, Ophthalmology, CM, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-4061-6542
Stefanie VeraaFaculty of Veterinary Medicine, Department Clinical Sciences, Diagnostic Imaging, Utrecht University, CM, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-1067-3976
Jos M EnsinkFaculty of Veterinary Medicine, Department Clinical Sciences, Equine Sciences, Equine Surgery and Orthopaedics, Utrecht University, CM, Utrecht, The Netherlands.
Utrecht University · NL

Funding

Utrecht University
6 · The paper itself

Abstract

backgroundIris cysts in horses are often asymptomatic and noticed incidentally. However, cysts can cause local corneal oedema and erratic behaviour like shying, decreased performance and head-shaking.

objectivesTo describe the use of diode laser as a noninvasive treatment option for iris cysts in the horse and to document factors influencing its efficacy, associated complications, long-term outcome and rate of recurrence. STUDY

designRetrospective case series.

methodsCase records of horses treated for iris cysts by diode laser at the Utrecht University Equine Clinic were reviewed between 2008 and 2020. Diagnosis was based on ophthalmic and ultrasonographic evaluation. Long-term follow-up was obtained in two phases, a telephone survey with the owner and a photographic re-evaluation of the treated eyes.

resultsThirty-five horses were included, with a total of 46 eyes treated. One day after diode laser treatment (short-term), 35/46 treated eyes had a good decrease in cyst size, 7/46 had a moderate effect, 1/46 had a minimal effect, 1/46 had no effect, and in two cases the effect was unspecified. The decrease in size after diode laser treatment in polycystic eyes (odds ratio [OR] 0.381, 95% CI 0.1530-0.724), p = 0.001), thick-walled cysts (OR = 0.139; CI = 0.023-0.726, p = 0.02) and hyperplastic corpora nigra (OR = 0.081; CI = 0.004-0.528, p = 0.03) was significantly less satisfactory, with ORs of 0.381, 0.139 and 0.081, respectively. Minor complications, such as mild reactive uveitis, were reported in 8/46 (17%) eyes. On long-term follow-up (median 19 months; IQR 25.5), clinical signs had diminished or disappeared in most cases (93%) and 83% of the owners would recommend the treatment. Based on long-term photographic re-evaluation (median 32.5 months; IQR 49.75), 2/16 cases of recurrence were seen. MAIN LIMITATIONS: Retrospective design, follow-up by telephone questionnaire and photographic re-evaluation. Loss to follow-up in the photographic re-evaluation.

conclusionsBoth short- and long-term results indicate diode laser treatment is a useful and safe option for iris cyst size reduction, with a low risk of recurrence. Presurgical ultrasonography is recommended to assess the feasibility of treatment and to allow for better surgical planning.

Indexed as

CystsHorse DiseasesAnimalsCorneaHorsesIrisLasers, SemiconductorRetrospective StudiesTreatment Outcomecorpora nigrahead-shakinghorselong-term follow-upophthalmology

Identifiers

PMID35575001
PMCPMC10083948
OpenAlexW4280513579

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.