Evidence map›Paper›PMID 35574761›Full record

ArticleACS chemical neuroscience2022

Paclitaxel and Urolithin A Prevent Histamine-Induced Neurovascular Breakdown Alike, in an

Srijayaprakash Uppada, Dianxiong Zou, Erin M Scott, Gladys Ko, Stephen Pflugfelder, M N V Ravi Kumar, Raghu Ganugula

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS chemical neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Srijayaprakash UppadaThe Center for Convergent Bioscience and Medicine (CCBM), The University of Alabama, Tuscaloosa, Alabama 35401, United States.
Dianxiong ZouCollege of Community Health Sciences, The University of Alabama, Tuscaloosa, Alabama 35401, United States.
Erin M ScottDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas 77843, United States.
Gladys KoVeterinary Integrative Biosciences, Texas A&M University, College Station, Texas 77843, United States.
Stephen PflugfelderCullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, Texas 77030, United States.
M N V Ravi KumarThe Center for Convergent Bioscience and Medicine (CCBM), The University of Alabama, Tuscaloosa, Alabama 35401, United States.ORCID 0000-0001-5606-401X
Raghu GanugulaThe Center for Convergent Bioscience and Medicine (CCBM), The University of Alabama, Tuscaloosa, Alabama 35401, United States.ORCID 0000-0003-0262-5170
University of Alabama · USTexas A&M University · USBaylor College of Medicine · US

Funding

Systemic anti-inflammatory therapy to prevent or delay diabetic cataracts and treat post-surgical inflammationR01EY028169 · NEI · UNIVERSITY OF ALABAMA IN TUSCALOOSA · PI MAJETI, RAVIKUMAR N · 2017 to 2022
$1.9M
Urolithin A nanoparticle therapy for acute kidney injuryR01DK128597 · NIDDK · UNIVERSITY OF ALABAMA IN TUSCALOOSA · PI ARORA, MEENAKSHI, MAJETI, RAVIKUMAR N · 2021 to 2025
$1.6M
NEI NIH HHS R01 EY028169NIDDK NIH HHS R01 DK128597
6 · The paper itself

Abstract

Neurovascular eye problems are better prevented than managed or treated. Despite growing concern of occurrence in aging populations and development secondary to diseases such as diabetes and hypertension, we currently have very few options to tackle this global problem. Creating effective and high-throughput screening strategies is as important as the intervention itself. Here, we present for the first time a robust

Indexed as

HistaminePaclitaxelAnimalsApoptosisCoumarinsRats3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-oneCoumarinsHistaminePaclitaxelapoptosishistaminepaclitaxelretinaurolithin Avasculature

Identifiers

PMID35574761
PMCPMC9928511
OpenAlexW4280498587

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.