Oxygen saturation and blood volume analysis by photoacoustic imaging to identify pre and post-PDT vascular changes.

M Atif, Atif Hanif, M S AlSalhi, S Devanesan, Haya Abdulaziz Altamimi

Open access · hybridAbstract read

In one paragraph

Article in Saudi journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.2field-weighted citation impact, top 55% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

Listening to Immunotherapy - Ultrasound and Photoacoustic Imaging Strategies to Guide and Enhance Cancer Treatments.Molecular imaging and biology · 2026
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

M AtifDepartment of Physics and Astronomy, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.

Atif HanifBotany and Microbiology Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.

M S AlSalhiDepartment of Physics and Astronomy, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.

S DevanesanDepartment of Physics and Astronomy, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.

Haya Abdulaziz AltamimiDepartment of Physics and Astronomy, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.

King Saud University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, the blood volume and oxygen saturation of tumors were measured after photoacoustic imaging (PAI) under conditions of pre-photodynamic therapy (PDT), post-PDT, and 4 hrs, and 24 hrs post-PDT. PDTs with aminolevulinic acid (ALA) and low and high doses of benzoporphyrin derivative (BPD) were conducted to observe oxygen saturation changes, and the rapid oxygen consumption in the blood detected due to the action of BPD at the vascular level resulted in the recovery of PDT completion. Likewise, blood volume changes followed by ALA-PDT and BPD-PDT at low and high doses depicted a fast expansion of the blood volume after treatment. The tumor subjected to a high dose of ALA-PDT showed a partial alteration of Hb-pO

Indexed as

Aminolevulinic acidBenzoporphyrin derivativeBioluminescenceBlood volumePhotoacoustic imaging

Identifiers

PMID35574285

DOI10.1016/j.sjbs.2022.103304

PMCPMC9092990

OpenAlexW4224235202

What OpenQuestion holds

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LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.