Evidence map›Paper›PMID 35574168›Full record

ArticleNeuro-ophthalmology (Aeolus Press)2022

Quantitative Evaluation of Pupil Responses in Patients with Prolactinomas Being Treated with Dopamine Agonists.

Sedat Ava, Leyla Hazar, Mine Karahan, Seyfettin Erdem, Mehmet Emin Dursun, Zafer Pekkolay, Uğur Keklikçi

Abstract read
In one paragraph

Article in Neuro-ophthalmology (Aeolus Press), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sedat AvaDepartment of Ophthalmology, Dicle University School of Medicine, Diyarbakır, Turkey.
Leyla HazarDepartment of Ophthalmology, Dicle University School of Medicine, Diyarbakır, Turkey.ORCID https://orcid.org/0000-0002-8206-781X
Mine KarahanDepartment of Ophthalmology, Dicle University School of Medicine, Diyarbakır, Turkey.
Seyfettin ErdemDepartment of Ophthalmology, Dicle University School of Medicine, Diyarbakır, Turkey.ORCID https://orcid.org/0000-0001-5742-1293
Mehmet Emin DursunDepartment of Ophthalmology, Dicle University School of Medicine, Diyarbakır, Turkey.
Zafer PekkolayDepartment of Endocrinology and Metabolism, Dicle University School of Medicine, Diyarbakır, Turkey.
Uğur KeklikçiDepartment of Ophthalmology, Dicle University School of Medicine, Diyarbakır, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to determine whether the dopamine agonist (DA) drug cabergoline used in the treatment of prolactinoma causes autonomic dysfunction by measuring static and dynamic pupillary responses. The study included 25 eyes from 25 patients who were receiving DA for the treatment of prolactinoma and 25 eyes from 25 healthy individuals. Static and dynamic pupillary responses were measured by automatic quantitative pupillometry. The scotopic pupillary diameter was found to be significantly higher in patients receiving DA medication compared with the control group, while pupil contraction time and pupillary dilatation latency were significantly lower. DA drug use changes static and dynamic pupillary responses, probably by increasing sympathetic tone. Pupillometry can be used as a non-invasive method to provide information about changes in the autonomic nervous system in patients receiving such drug therapy.

Indexed as

cabergolinedopaminedynamic pupillary responseProlactinomastatic pupillary response

Identifiers

PMID35574168
PMCPMC9103269

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.