ArticleCurrent opinion in biomedical engineering2022
Tissue Engineering for Cervical Function in Pregnancy.
Article in Current opinion in biomedical engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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0 citing papers in PubMed.
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Authors and funding
3 authors.
Funding
Abstract
Cervical insufficiency is a significant obstetrical complication that causes preterm birth. The current treatment of cervical insufficiency is cerclage surgery. A cerclage is a suture that is placed around the cervix to provide compression support. The load bearing portion of the cervix is the stroma, which is composed of collagen-rich extracellular matrix. A remarkable feature of the cervix is progressive softening throughout gestation. The biochemical mechanisms of cervical softening, however, are poorly understood. In this narrative review, we discuss our approach to using tissue engineering techniques to study cervical function in pregnancy. A brief review of the clinical significance of the cervix in pregnancy is presented. The development of a tissue engineering model for studying cervical remodeling is discussed. We also discuss an engineered injectable hydrogel as an alternate treatment for cervical dysfunction. We advocate for a bioengineering approach to study cervical dysfunction in pregnancy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.