Evidence map›Paper›PMID 35573945›Full record

ArticleFrontiers in pediatrics2022

Periconceptional Folic Acid Supplementation and Newborn Birth Weights.

Jing Lin, Cheng Wang, Sisi Li, Jie Zhang, Lei Jin, Mingkun Tong, Wenying Meng, Aiguo Ren, Lei Chen, Lei Jin

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jing LinDepartment of Obstetrics and Gynecology, The Sixth Medical Center of People's Liberation Army (PLA) General Hospital, Beijing, China.
Cheng WangInstitute of Reproductive and Child Health, Peking University/Key Laboratory of Reproductive Health, The National Health Commission of the People's Republic of China, Beijing, China.
Sisi LiInstitute of Reproductive and Child Health, Peking University/Key Laboratory of Reproductive Health, The National Health Commission of the People's Republic of China, Beijing, China.
Jie ZhangInstitute of Reproductive and Child Health, Peking University/Key Laboratory of Reproductive Health, The National Health Commission of the People's Republic of China, Beijing, China.
Lei JinTongzhou Maternal and Child Health Care Hospital of Beijing, Beijing, China.
Mingkun TongInstitute of Reproductive and Child Health, Peking University/Key Laboratory of Reproductive Health, The National Health Commission of the People's Republic of China, Beijing, China.
Wenying MengTongzhou Maternal and Child Health Care Hospital of Beijing, Beijing, China.
Aiguo RenInstitute of Reproductive and Child Health, Peking University/Key Laboratory of Reproductive Health, The National Health Commission of the People's Republic of China, Beijing, China.
Lei ChenDepartment of Obstetrics and Gynecology, The Sixth Medical Center of People's Liberation Army (PLA) General Hospital, Beijing, China.
Lei JinInstitute of Reproductive and Child Health, Peking University/Key Laboratory of Reproductive Health, The National Health Commission of the People's Republic of China, Beijing, China.
Peking University · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The relationship between maternal folic acid supplementation and the birth weights of offspring remains inconclusive. Aim: To examine the associations between maternal supplementation with folic acid only (FAO) or multiple micronutrients containing folic acid (MMFA) and newborn birth weights, as well as the risk of small for gestational week age (SGA) and large for gestational week age (LGA) newborns. Methods: Data on 31,107 births from 2015 to 2018 were extracted from the population-based prenatal health care system in a district of Beijing. Generalized linear and logistic regression models were used to evaluate the association between maternal periconceptional folic acid supplementation and birth weights or with risk of small for gestational week age (SGA) and large for gestational week age (LGA). Results: Compared with newborns whose mothers did not use any folic acid supplements, the newborns with maternal periconceptional folic acid supplementation had similar median birth weight but had a lower risk of SGA [adjusted odds ratio ( Conclusion: Periconceptional FAO supplementation has no impact on the median birth weight of offspring and the risk of LGA. Compared with FAO, MMFA supplementation may increase the average birth weight, and a high compliance of supplementation with FAO or MMFA may reduce the risk of SGA, with MMFA having ad stronger effect than FAO.

Indexed as

birth weightfolic acidlarge-for-gestational-agemicronutrientspregnancysmall-for-gestational-agevitamin

Identifiers

PMID35573945
PMCPMC9096220
OpenAlexW4224986608

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.