ArticleFrontiers in cellular and infection microbiology2022
Trends and Developments in the Detection of Pathogens in Central Nervous System Infections: A Bibliometric Study.
Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Bibliometric analysis of research trends and prospective directions ofFrontiers in microbiology · 2025Pooled it
- Metagenomic next-generation sequencing in diagnosing rhino-orbital-cerebral mucormycosis presenting as cerebral Infarction: a case series and diagnostic analysis of seven patients.Frontiers in fungal biology · 2026Article
- Antimicrobial resistance and microbiological gap analysis for central nervous system-assocaited bacterial pathogens in Nigeria.Frontiers in microbiology · 2026Article
- Detection of dengue virus encephalitis in central part of Sri Lanka.World journal of virology · 2025Article
- Comprehensive Analysis of the Biomechanical Research of Pelvic Organ Prolapse: A Scientometric Approach.Journal of multidisciplinary healthcare · 2025Article
- Bibliometric analysis and visualization of lipid droplets in the central nervous system: research hotspots and Frontiers (2000-2024).Frontiers in aging neuroscience · 2025Article
- Solving the diagnostic dilemma in bone infections: metagenomic next generation sequencing enhances pathogen identification accuracy.Frontiers in medicine · 2025Article
- Review
- Clinical presentation, management, and outcome of suspected central nervous system infections in Indonesia: a prospective cohort study.Infection · 2024Article
- Emerging trends and hotspots of the itch research: A bibliometric and visualized analysis.CNS neuroscience & therapeutics · 2024Article
- Liquid Biopsy in Neurological Diseases.Cells · 2023Review
- Bibliometric and Visualization Analysis of Biomechanical Research on Lumbar Intervertebral Disc.Journal of pain research · 2023Article
- Microbial signatures of neonatal bacterial meningitis from multiple body sites.Frontiers in cellular and infection microbiology · 2023Article
- Bibliometric and visual analysis of research on the links between the gut microbiota and pain from 2002 to 2021.Frontiers in medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Rapid, sensitive, and specific laboratory assays are critical for the diagnosis and management of central nervous system (CNS) infections. The purpose of this study is to explore the intellectual landscape of research investigating methods for the detection of pathogens in patients with CNS infections and to identify the development trends and research frontier in this field. Methods: A bibliometric study is conducted by analyzing literature retrieved from the Web of Science (WoS) Core Collection Database for the years 2000 to 2021. CiteSpace software is used for bibliometric analysis and network visualization, including co-citation analysis of references, co-occurrence analysis of keywords, and cooperation network analysis of authors, institutions, and countries/regions. Results: A total of 2,282 publications are eventually screened, with an upward trend in the number of publications per year. The majority of papers are attributed to the disciplines of MICROBIOLOGY, INFECTIOUS DISEASES, IMMUNOLOGY, NEUROSCIENCES & NEUROLOGY, and VIROLOGY. The co-citation analysis of references shows that recent research has focused on the largest cluster "metagenomic next-generation sequencing"; the results of the analysis of the highest-cited publications and the citation burst of publications reveal that there is a strong interest stimulated in metagenomic next-generation sequencing. The co-occurrence analysis of keywords indicates that "infection", "pathogen", "diagnosis", "gene", "virus", "polymerase chain reaction", "cerebrospinal fluid", "epidemiology", and "metagenomic next-generation sequencing" are the main research priorities in the field of pathogen detection for CNS infections, and the keyword with the highest strength of burst is "metagenomic next-generation sequencing". Collaborative network analysis reveals that the USA, the Centers for Disease Control and Prevention of USA, and XIN WANG and JENNIFER DIEN BARD are the most influential country, institution, and researchers, respectively. Conclusions: Exploring more advanced laboratory assays to improve the diagnostic accuracy of pathogens is essential for CNS infection research. Metagenomic next-generation sequencing is emerging as a novel useful unbiased approach for diagnosing infectious diseases of the CNS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.