Evidence map›Paper›PMID 35573684›Full record

ArticleFrontiers in cell and developmental biology2022

Virally Mediated Connexin 26 Expression in Postnatal Scala Media Significantly and Transiently Preserves Hearing in Connexin 30 Null Mice.

Li Zhang, Wenwen Wang, Sun Myoung Kim, Jianjun Wang, Binfei Zhou, Weijia Kong, James Zheng, Xi Lin

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. IsMedComm · 2025
    Article
  3. Article
  4. Advancing precision ear medicine: leveraging animal models for disease insights and therapeutic innovations.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Review
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Li ZhangDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wenwen WangDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Sun Myoung KimDepartment of Otolaryngology, Emory University School of Medicine, Atlanta, GA, United States.
Jianjun WangDepartment of Otolaryngology, Emory University School of Medicine, Atlanta, GA, United States.
Binfei ZhouDepartment of Otolaryngology, Emory University School of Medicine, Atlanta, GA, United States.
Weijia KongDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
James ZhengDepartment of Otolaryngology, Emory University School of Medicine, Atlanta, GA, United States.
Xi LinDepartment of Otolaryngology, Emory University School of Medicine, Atlanta, GA, United States.
Emory University · USHuazhong University of Science and Technology · CNUnion Hospital · CN

Funding

Gene Therapy for Treating Human Genetic Deafness Tested in Animal ModelsR01DC014496 · NIDCD · EMORY UNIVERSITY · PI ZHENG, JAMES Q · 2016 to 2020
$2.4M
Hearing Restoration by Virally Expressing Mechano-Sensitive Channels in Spiral Ganglion NeuronsR21DC017272 · NIDCD · EMORY UNIVERSITY · PI ZHENG, JAMES Q · 2019 to 2020
$429k
NIDCD NIH HHS R01 DC014496NIDCD NIH HHS R21 DC017272
6 · The paper itself

Abstract

Non-sensory cells in the sensory epithelium of the cochlea are connected extensively by gap junctions. Functionally null mutations in

Indexed as

cochleaconnexingene therapyhearing sensitivitymousescala mediavirus

Identifiers

PMID35573684
PMCPMC9091169
OpenAlexW4224940297

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.