Evidence map›Paper›PMID 35573503›Full record

ReviewCureus2022

Vitamin D: The Missing Nutrient Behind the Two Deadly Pandemics, COVID-19 and Cardiovascular Diseases.

Abhishek Singh, Anusha Chidharla, Kriti Agarwal, Priyanka Singh, Nidhi Jain, Gashaw Hassen, Salwa Abdelwahed, Renu Bhandari, Kajal Patel, Sachin Gupta and 2 more

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Impact of different milling techniques towards vitamin DJournal of food science and technology · 2025
    Article
  2. Vitamin D status and clinical implications in the adult population of Malaysia: a position paper by the Malaysian Vitamin D Special Interest Group.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 3 countries.

Abhishek SinghInternal Medicine, Saint Vincent Hospital, Worcester, USA.
Anusha ChidharlaHematology Oncology, University of Kansas Medical Center, Kansas, USA.
Kriti AgarwalDepartment of Internal Medicine, Hackensack Meridian Health, Palisades Medical Center, North Bergen, USA.
Priyanka SinghMedicine, Smolensk State Medical University, Smolensk, RUS.
Nidhi JainMedicine and Surgery, Himalayan Institute of Medical Sciences, Dehradun, IND.
Gashaw HassenInternal Medicine, Mercy Medical Center, Baltimore, USA.
Salwa AbdelwahedDepartment of Family and Community Medicine, University of Missouri Kansas City School of Medicine, Kansas City, USA.
Renu BhandariInternal Medicine, Manipal College of Medical Sciences, Kaski, NPL.
Kajal PatelDepartment of Internal Medicine, Smt. Kashibai Navale Medical College and General Hospital, Nahre, IND.
Sachin GuptaInternal Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, USA.
Thoyaja KoritalaInternal Medicine, Mayo Clinic, Mankato, USA.
Rizwan RabbaniNephrology, Temple University Hospital, Philadelphia, USA.
California Institute of Behavioral Neurosciences and Psychology (United States) · USHackensack Meridian Health · USHimalayan Institute of Yoga Science and Philosophy · USMercy Medical Center · USPenn State Milton S. Hershey Medical Center · USSaint Vincent Hospital · USTemple University Hospital · USWinnMed · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus (COVID-19) pandemic is claiming millions of lives and creating an additional burden on health care, which is already affected by the rise of non-communicable diseases (NCDs). The scientific community, on the other side, is enormously engaged with studies to best identify the characteristics of the virus and minimize its effect while supporting the fight to contain NCDs, mainly cardiovascular diseases (CVDs), which are contributing hugely to the global death toll. Hence, the roles of vitamin D in COVID-19 immunity and cardiovascular health are gaining traction recently.  This literature review will mainly focus on summarizing pertinent studies and scientific publications which highlight the association of vitamin D levels with the various outcomes of COVID-19 and CVDs. It will also address how low vitamin D correlates with the epidemiology of CVDs and the inflammatory mechanisms attributed to COVID-19 severity. We believe that our review may open up hindsight perspectives and further discussions among the physicians in tapping the potential of vitamin D supplementation to tackle the morbidity, mortality, and health care cost of the two deadly diseases, COVID-19 and CVDs.

Indexed as

acute myocardial infarction (ami)coronary heart disease (chd)covid 19cytokinescytokine storm syndromeicu admissionsperipheral arterial disease (pad)strokevitamin-dvitamin-d deficiency

Identifiers

PMID35573503
PMCPMC9106532
OpenAlexW4224076269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.