Evidence map›Paper›PMID 35573425›Full record

ArticleThe Pan African medical journal2022

Socio-economic status and the risk of breast cancer among Nigerian women: a case control study.

Samuel Onyinyechukwu Azubuike, Louise Hayes, Linda Sharp, Adewumi Alabi, Rasaaq Oyesegun, Richard McNally

Open access · goldAbstract read
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Article in The Pan African medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Samuel Onyinyechukwu AzubuikeDepartment of Public Health, Faculty of Health Sciences, National Open University of Nigeria, Abuja, Nigeria.
Louise HayesPopulation Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Linda SharpPopulation Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Adewumi AlabiDepartment of Radiation Biology, Radiotherapy and Radiodiagnosis, College of Medicine, Lagos University Teaching Hospital, Lagos, Nigeria.
Rasaaq OyesegunDepartment of Radiotherapy and Oncology, National Hospital, Abuja, Nigeria.
Richard McNallyPopulation Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Newcastle University · GBNational Hospital Abuja · NGUniversity of Lagos · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: an increased risk of breast cancer associated with high socio-economic status has been reported in high income countries. A few available African studies have reported inconsistent findings using different single socio-economic measures. Our aim was to investigate the association between socio-economic status and the risk of breast cancer among Nigerian women based on a range of socio-economic status measures. Methods: we conducted a hospital-based case-control study involving participants from five hospitals in Lagos and Abuja. Women were interviewed in-person between October 2016 and May 2017 using a semi-structured questionnaire. Socio-economic status was assessed based on education, occupation, income, wealth, and socio-economic index. Multivariable logistic regression was applied in data analysis using Statistical Package for Social Sciences (SPSS) version 23. Level of significance was based on 95% confidence interval or p-values less than 0.05. Results: we recruited 379 histologically confirmed breast cancer cases and 403 controls. Following full adjustments, breast cancer risk reduced as socio-economic index increased (p for trend=0.028). Although women in the highest categories of educational attainment [Odds ratio (OR)=0.21, 95% confidence interval (CI): 0.09, 0.53], and personal income (OR=0.37, 95% CI: 0.19, 0.72) had a reduced risk of breast cancer compared to women in the lowest categories respectively after adjustments for relevant covariates, income alone exhibited a significant risk reduction following mutual adjustment for other socio-economic status measures (p for trend=0.014). Conclusion: the observed associations between high socio-economic status and lower breast cancer risk in Nigeria contrast with predominant findings in high-income countries. It suggests the need for socio-economic intervention and other preventive programmes such as improved access to screening and diagnostic services targeted at women of low socio-economic status in Nigeria.

Indexed as

Breast NeoplasmsCase-Control StudiesEconomic StatusEducational StatusFemaleHumansNigeriaSocioeconomic FactorsBreast cancerNigeriarisk factorsocio-economic statussub-Saharan Africawomen

Identifiers

PMID35573425
PMCPMC9074071
OpenAlexW4214941478

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.