Evidence map›Paper›PMID 35573278›Full record

ReviewFrontiers in toxicology2022

Considerations for Improving Metabolism Predictions for

Marjory Moreau, Pankajini Mallick, Marci Smeltz, Saad Haider, Chantel I Nicolas, Salil N Pendse, Jeremy A Leonard, Matthew W Linakis, Patrick D McMullen, Rebecca A Clewell and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. A CYP3A7 metabolically competent human induced pluripotent stem cell-derived hepatocyte-like cell (hHLCDrug metabolism and disposition: the biological fate of chemicals · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Identifying xenobiotic metabolites withFrontiers in toxicology · 2023
    Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Marjory MoreauScitoVation, LLC, Durham, NC, United States.
Pankajini MallickScitoVation, LLC, Durham, NC, United States.
Marci SmeltzScitoVation, LLC, Durham, NC, United States.
Saad HaiderScitoVation, LLC, Durham, NC, United States.
Chantel I NicolasScitoVation, LLC, Durham, NC, United States.
Salil N PendseScitoVation, LLC, Durham, NC, United States.
Jeremy A LeonardOak Ridge Institute for Science and Education, Oak Ridge, TN, United States.
Matthew W LinakisRamboll US Corp., Research Triangle Park, NC, United States.
Patrick D McMullenScitoVation, LLC, Durham, NC, United States.
Rebecca A Clewell21st Century Tox Consulting, Chapel Hill, NC, United States.
Harvey J ClewellRamboll US Corp., Research Triangle Park, NC, United States.
Miyoung YoonScitoVation, LLC, Durham, NC, United States.
Triangle · USOak Ridge Associated Universities · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-throughput (HT)

Indexed as

HT-IVIVEin vitroIVIVEmetabolismQSARrisk assessment

Identifiers

PMID35573278
PMCPMC9099212
OpenAlexW4225130328

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.