Evidence map›Paper›PMID 35573153›Full record

ArticleImmune network2022

Obesity Exacerbates Coxsackievirus Infection via Lipid-Induced Mitochondrial Reactive Oxygen Species Generation.

Seong-Ryeol Kim, Jae-Hyoung Song, Jae-Hee Ahn, Myeong Seon Jeong, Yoon Mee Yang, Jaewon Cho, Jae-Hyeon Jeong, Younggil Cha, Kil-Nam Kim, Hong Pyo Kim and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Immune network, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Seong-Ryeol KimDepartment of Pharmacy, Kangwon National University, Chuncheon 24341, Korea.
Jae-Hyoung SongDepartment of Pharmacy, Kangwon National University, Chuncheon 24341, Korea.
Jae-Hee AhnDepartment of Pharmacy, Kangwon National University, Chuncheon 24341, Korea.
Myeong Seon JeongChuncheon Center, Korea Basic Science Institute (KBSI), Chuncheon 24341, Korea.
Yoon Mee YangDepartment of Pharmacy, Kangwon National University, Chuncheon 24341, Korea.
Jaewon ChoDepartment of Pharmacy, Kangwon National University, Chuncheon 24341, Korea.
Jae-Hyeon JeongDepartment of Pharmacy, Kangwon National University, Chuncheon 24341, Korea.
Younggil ChaDepartment of Pharmacy, Kangwon National University, Chuncheon 24341, Korea.
Kil-Nam KimChuncheon Center, Korea Basic Science Institute (KBSI), Chuncheon 24341, Korea.
Hong Pyo KimCollege of Pharmacy, Ajou University, Suwon 16499, Korea.
Sun-Young ChangCollege of Pharmacy, Ajou University, Suwon 16499, Korea.
Hyun-Jeong KoDepartment of Pharmacy, Kangwon National University, Chuncheon 24341, Korea.ORCID https://orcid.org/0000-0002-3844-928X
Kangwon National University · KRAjou University · KRKorea Basic Science Institute · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coxsackievirus B3 (CVB3) infection causes acute pancreatitis and myocarditis. However, its pathophysiological mechanism is unclear. Here, we investigated how lipid metabolism is associated with exacerbation of CVB3 pathology using high-fat diet (HFD)-induced obese mice. Mice were intraperitoneally inoculated with 1×10

Indexed as

Coxsackievirus B3Lipid metabolismMitochondriaMitoquinoneObesityReactive oxygen species

Identifiers

PMID35573153
PMCPMC9066006
OpenAlexW4280594169

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.