ReviewFrontiers in medicine2022
New Insights in Pathogenesis of Endometriosis.
Review in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- Alterations in Cellular Immunity in Patients With Endometriosis: Systematic Review and Meta-Analysis.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026Pooled it
- The impact of endometriosis on depressive and anxiety symptoms and quality of life: a systematic review.Frontiers in public health · 2023Pooled it
- The Endocannabinoid System in Endometriosis-Associated Pain: Mechanisms, Molecular Targets, and Therapeutic Implications.Reproductive sciences (Thousand Oaks, Calif.) · 2026Review
- Endometriosis of the vermiform appendix: a rare cause of acute abdomen in women - case report and review of literature.International journal of surgery case reports · 2026Article
- Differential Antioxidant Capacities of Human Endometriotic and Endometrial Cell Models Under HInternational journal of molecular sciences · 2026Article
- Navigating complexity: review and updates of endometriosis and adenomyosis imaging.The British journal of radiology · 2026Review
- From local lesion to multisystem disease: integrated crosstalk among the gut microbiota, immune system, and host metabolism in endometriosis.Frontiers in immunology · 2026Review
- 'I Wish I Fought for Myself More Instead of Just Letting Doctors Dismiss Me': A Combined Qualitative Analysis of Four Cohorts of Aotearoa New Zealand Endometriosis Patients.The Australian & New Zealand journal of obstetrics & gynaecology · 2025Article
- The interplay between endometriosis and obesity.Trends in endocrinology and metabolism: TEM · 2025Review
- Dual Targeting of Orphan Nuclear Receptors NR4A1 and NR4A2 for Nonhormonal Endometriosis Therapy.Endocrinology · 2025Article
- The Role of Nutrition in Endometriosis Prevention and Management: A Comprehensive Review.International journal of fertility & sterility · 2025Review
- Understanding Endometriosis: A Broad Review of Its Causes, Management, and Impact.International journal of molecular sciences · 2025Review
- 'The Difficulty of Diagnosis Compromises Patient Care for People With Endometriosis': Interview Study With Aotearoa New Zealand General Practitioners.Health expectations : an international journal of public participation in health care and health policy · 2025Article
- Review
- Intra-ovarian injection of autologous menstrual blood-derived-mesenchymal stromal cells: a safe and promising method to improve pregnancy rate in poor ovarian responders.Stem cell research & therapy · 2025Observational
- Analysis of the Biopsychosocial Impacts Associated with Endometriosis to Improve Patient Care.Journal of clinical medicine · 2025Review
- The Role of Adenogenesis Factors in the Pathogenesis of Endometriosis.International journal of molecular sciences · 2025Review
- Comprehensive Management of Bowel Endometriosis: Surgical Techniques, Outcomes, and Best Practices.Journal of clinical medicine · 2025Review
- Real world perspectives on endometriosis disease phenotyping through surgery, omics, health data, and artificial intelligence.npj women's health · 2025Review
- Bioinformatics Analysis of Hypoxia-Related Mechanisms in Endometriosis: DDR2 as a Potential Diagnostic and Therapeutic Biomarker.BioMed research international · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endometriosis is a gynecological disease characterized by the growth of endometrial glands and stroma outside the uterine cavity. The incidence of the disease is very high, there are currently no reliable early diagnostic tests, the therapies are only symptomatic and, consequently, the social impact of endometriosis is very important, also considering the related fertility problems. Despite this, the pathogenesis of endometriosis is still not fully defined. Retrograde menstruation and coelomic metaplasia are currently the most recognized pathogenetic hypotheses. Recent experimental evidences generated by our research group and by others have indicated an alteration of the fine-tuning of the female genital system developmental program during a critical window of time in the fetal life as the pathogenetic event prompting to the development of endometriosis later in life. Goal of this article is to present a revision of the recent literature about the different pathogenetic mechanisms proposed for endometriosis with particular emphasis on the embryologic theory. The possible clinical and pathological implications of these findings will be discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.