Evidence map›Paper›PMID 35572889›Full record

ArticleJournal of thoracic disease2022

Identification and

Xiaopeng Zhao, Chong Yuan, Xu He, Miao Wang, Haoran Zhang, Jingge Cheng, Hongyan Wang

Open access · diamondAbstract read
In one paragraph

Article in Journal of thoracic disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiaopeng ZhaoDepartment of Thoracic Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Chong YuanThe First Outpatient Department Directly Under Hebei Province, Shijiazhuang, China.
Xu HeDepartment of Thoracic Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Miao WangDepartment of Thoracic Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Haoran ZhangDepartment of Thoracic Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Jingge ChengDepartment of Thoracic Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Hongyan WangDepartment of Thoracic Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Hebei Medical University · CNFourth Hospital of Hebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The aim of the present study was to find diagnostic and prognostic biomarkers for lung squamous cell carcinoma (LUSC) and to validate key biomarkers Methods: RNA sequencing was used to identify differentially expressed mRNAs (DEmRNAs) and differentially expressed long non-coding RNAs (DElncRNAs) in LUSC tissues. RNA sequencing results were validated using a published dataset. Diagnostic and prognostic values of candidate genes were evaluated by receiver-operating characteristic (ROC) curve analysis and survival analysis, respectively. To determine the effect of Results: In total, 1,946 DEmRNAs and 428 DElncRNAs were identified in LUSC compared with normal tissues. A total of 851 DElncRNA-DEmRNA co-expression pairs were obtained. With the exception of Conclusions: The findings of the present study could help determine the pathogenesis of LUSC and provide new and accurate therapeutic targets for its treatment.

Indexed as

co-expressiondifferentially expressed long non-coding RNAs (DElncRNAs)differentially expressed mRNAs (DEmRNAs)Lung squamous cell carcinoma (LUSC)RNA sequencing

Identifiers

PMID35572889
PMCPMC9096289
OpenAlexW4280567991

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.