Evidence map›Paper›PMID 35572814›Full record

ArticleResearch and reports in urology2022

The Correlation Between Platelet Count and Survival in Prostate Cancer.

Tünde Mezei, Imre Bőde, Péter Tenke, Valéria Jósa, Keresztély Merkel, Zsuzsanna Szilasi, Attila Tordai, Domokos Máthé, Zsolt Baranyai

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Article in Research and reports in urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Tünde MezeiDepartment of Urology, Jahn Ferenc South-Pest Hospital, Budapest, Hungary.ORCID 0000-0002-9880-7018
Imre BődeDepartment of Urology, Jahn Ferenc South-Pest Hospital, Budapest, Hungary.
Péter TenkeDepartment of Urology, Jahn Ferenc South-Pest Hospital, Budapest, Hungary.
Valéria JósaDepartment of Otorhinolaryngology and Head and Neck Surgery, Jahn Ferenc South-Pest Hospital, Budapest, Hungary.
Keresztély MerkelDepartment of Surgery, Szent Imre Hospital, Budapest, Hungary.
Zsuzsanna SzilasiDepartment of Otorhinolaryngology and Head and Neck Surgery, HDF Medical Centre, Budapest, Hungary.
Attila TordaiInstitute of Pathophysiology, Semmelweis University, Budapest, Hungary.
Domokos MáthéDepartment of Biophysics and Radiation Biology, Semmelweis University, Budapest, Hungary.
Zsolt BaranyaiSemmelweis University, Department of Transplantation and Surgery, Budapest, Hungary.
Jahn Ferenc Dél-Pesti Kórház és Rendelőintézet · HUSemmelweis University · HUHUN-REN Veterinary Medical Research Institute · HUSzent Imre Egyetemi Oktatókórház · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: A number of studies have confirmed that elevated platelet count accompanying various solid tumours is associated with worse survival. However, only meagre data are available on the relationship between thrombocytosis and survival in prostate cancer. Methods: We conducted a retrospective analysis on clinical-pathological data accumulated from 316 patients during on average 51 months of follow-up after laparoscopic prostatectomy performed for prostate cancer. We analyzed the relationship between platelet count, risk factors, prostate-specific antigen (PSA) and cancer stage with use the Tumor, Node, Metastase system (TNM), as well as surgical margin, and prognosis. Results: Thrombocytosis occurred in only one out of the 316 patients. The multivariate Cox proportional hazard model showed that preoperative PSA, risk group, preoperative haemoglobin level, and surgical margin status were significant, independent predictors of biochemical progression-free survival. By contrast, age at diagnosis and thrombocytosis had no such predictive value. Conclusion: We could not demonstrate an association between elevated platelet count and worse survival in our study population of patients with prostate cancer.

Indexed as

pathomechanismprognosisprostate cancersolid tumorthrombocytosis

Identifiers

PMID35572814
PMCPMC9092472
OpenAlexW4229065858

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.