ArticleGeneral psychiatry2022
Impact of adverse childhood experiences on the symptom severity of different mental disorders: a cross-diagnostic study.
Article in General psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 36 citations in OpenAlex.
- Childhood Adversities and the ATTACHInternational journal of environmental research and public health · 2024Trial
- Adverse childhood experiences and neurodevelopmental disorder traits: A nationwide cross-sectional study.PCN reports : psychiatry and clinical neurosciences · 2026Article
- Effectiveness of Deep Brain Stimulation for Treatment-Resistant OCD: Systematic Review of Anatomical Targets and Meta-Analysis of Randomized and Non-Randomized Studies.Brain sciences · 2026Review
- Adverse Childhood Experiences and Adolescent Mental Health Symptoms: The Role of Peer Interactions.Journal of child & adolescent trauma · 2026Article
- Mental illness severity and characteristics among holocaust survivor immigrants, Non-Holocaust immigrants, and native israelis: A historical prospective study.Social psychiatry and psychiatric epidemiology · 2026Article
- Prevalence of Adverse Childhood Experiences : A Cross-Sectional Study among Inpatients at Ndera Neuropsychiatric Teaching Hospital in Rwanda.Rwanda journal of medicine and health sciences · 2026Article
- Key protective factors that mitigate the impact of childhood trauma on poor mental health in adulthood: a scoping review protocol.BMJ open · 2026Article
- Educational Gaps in Epigenetics: A Cross-Sectional Study of Health Sciences Students' Knowledge and Perceptions in Saudi Arabia.Advances in medical education and practice · 2026Article
- Preconception mental health (Healthy Life Trajectories Initiative): Identifying factors associated with probable anxiety and depression among young women living in urban-poor South Africa.PLOS mental health · 2026Article
- The Relationship Between Childhood Trauma and Mental Health in Indian Undergraduate Students: A Cross-sectional Study.Indian journal of psychological medicine · 2025Article
- The Interplay Between Juvenile Delinquency and ADHD: A Systematic Review of Social, Psychological, and Educational Aspects.Behavioral sciences (Basel, Switzerland) · 2025Review
- Adverse childhood experiences and chronic health outcomes: evidence from 33 US states in the Behavioral Risk Factor Surveillance System, 2019-2023.BMC public health · 2025Article
- Adverse childhood experiences and hypertension: examining the roles of depressive symptoms and cardiometabolic dysregulations based on CHARLS data.Frontiers in public health · 2025Article
- Impact of childhood trauma on cognitive function in patients with bipolar disorder.Frontiers in psychiatry · 2025Article
- Digital Health Innovations for Screening and Mitigating Mental Health Impacts of Adverse Childhood Experiences: Narrative Review.JMIR pediatrics and parenting · 2024Review
- Trends in prevalence of adverse childhood experiences by sociodemographic factors in the United States: Behavioral Risk Factor Surveillance System 2009-2022.BMC public health · 2024Article
- Effects of expanded adverse childhood experiences including school bullying, childhood poverty, and natural disasters on mental health in adulthood.Scientific reports · 2024Article
- Adverse Childhood Experiences, Coping and Resilience in Persons with Alcohol Use Disorder and Their Non-drinking Siblings in High-density Families: A Case-control Study.Indian journal of psychological medicine · 2024Article
- Childhood maltreatment and personality disorders in adolescents and adults with psychotic or non-psychotic disorders.Frontiers in psychiatry · 2024Article
- Psychiatric comorbidities in epilepsy: population co-occurrence, genetic correlations and causal effects.General psychiatry · 2024Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Adverse childhood experiences have a significant impact on different mental disorders. Objective: To compare differences in adverse childhood experiences among those with different mental disorders and their relationships in a cross-disorder manner. Methods: The study included 1513 individuals aged ≥18 years : 339 patients with substance use disorders, 125 patients with schizophrenia, 342 patients with depression, 136 patients with bipolar disorder, 431 patients with obsessive-compulsive disorder (OCD), and 140 healthy controls. The Early Trauma Inventory Self Report-Short Form was used to investigate childhood traumatic experiences, and the Addiction Severity Index, Positive and Negative Syndrome Scale, Hamilton Depression Scale, Young Mania Rating Scale, and Yale-Brown Obsessive-Compulsive Scale were used to assess mental disorder severity. Correlation and multivariate logistic regression were analysed between adverse childhood experiences and clinical features. Results: Levels of adverse childhood experiences were significantly different among different mental disorders. Moreover, 25.8% of patients with substance use disorders reported childhood trauma, which was significantly higher than found in the other four psychiatric disorder groups. Emotional abuse scores were positively correlated with disease severity: the higher the total trauma score, the more severe the mental disorder. Conclusions: Adverse childhood experiences are a common phenomenon in those with mental disorders, and the level of trauma affects mental disorder severity. Emotional abuse is closely related to many mental disorders. The incidence or severity of mental disorders can be reduced in the future by reducing the incidence of adverse childhood experiences or by timely intervention in childhood trauma.
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