Evidence map›Paper›PMID 35572766›Full record

ReviewSynthetic and systems biotechnology2022

Synthetic biology techniques to tackle heavy metal pollution and poisoning.

Adithi Somayaji, Soumodeep Sarkar, Shravan Balasubramaniam, Ritu Raval

Abstract readReview
In one paragraph

Review in Synthetic and systems biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Adithi SomayajiDepartment of Biotechnology, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, India.
Soumodeep SarkarDepartment of Biotechnology, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, India.
Shravan BalasubramaniamDepartment of Biotechnology, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, India.
Ritu RavalDepartment of Biotechnology, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The requirement for natural resources and energy increases continually with the increase in population. An inevitable result of this is soil, water, and air pollution with diverse pollutants, including heavy metals. Synthetic Biology involves using modular, interchangeable biological parts, devices in standard chassis or whole organisms to achieve a programmed result that can be quantified and optimized till it meets the required efficiency. This makes synthetic biology techniques very popular to tackle pressing global issues such as heavy metal poisoning. This review aimed to highlight various advancements as well as benefits, risks, and problems in synthetic biology techniques for detection, bioaccumulation, and biosorption of various heavy metals using engineered organisms. We found that while such an approach is cost-effective, accessible, and efficient, there are several inherent technological and ethical issues including but not limited to metabolic burden and consequences of use of genetically modified organisms respectively. Overcoming these hurdles will probably take time and innumerable conversations, and should be done through education and a culture of responsible research, rather than enforcing restrictions on the development of synthetic biology.

Indexed as

BioremediationBiosensorsHeavy metalsResponsible researchSynthetic biology

Identifiers

PMID35572766
PMCPMC9078997

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.