Evidence map›Paper›PMID 35572727›Full record

ArticleBioMed research international2022

6'-O-Galloylpaeoniflorin Exerts Inhibitory Bioactivities in Human Neuroblastoma Cells via Modulating AMPK/miR-489/XIAP Pathway.

Lijun Zhou, Aiwu Li, Qiangye Zhang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lijun ZhouDepartment of Pediatric Surgery, Qilu Hospital of Shandong University, Jinan 250012, China.ORCID https://orcid.org/0000-0003-4400-8939
Aiwu LiDepartment of Pediatric Surgery, Qilu Hospital of Shandong University, Jinan 250012, China.ORCID https://orcid.org/0000-0002-1069-2026
Qiangye ZhangDepartment of Pediatric Surgery, Qilu Hospital of Shandong University, Jinan 250012, China.ORCID https://orcid.org/0000-0002-8819-9493
Qilu Hospital of Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although therapies against neuroblastoma (NBM) have advanced, the patients still suffer from poor prognoses due to distal metastasis or the occurrence of multidrug resistance. Accumulating evidence has proved that chemicals derived from natural products possess potent anti-NBM properties or can be used as adjuvants for chemotherapy. In the present study, we demonstrated that 6'-O-galloylpaeoniflorin (GPF), a galloylated derivative of paeoniflorin isolated from the roots of

Indexed as

MicroRNAsNeuroblastomaAMP-Activated Protein KinasesApoptosisBridged Bicyclo Compounds, HeterocyclicCell Line, TumorGlucosidesHumansMonoterpenesX-Linked Inhibitor of Apoptosis ProteinAMP-Activated Protein KinasesBridged Bicyclo Compounds, HeterocyclicgalloylpaeoniflorinGlucosidesMicroRNAsMIRN489 microRNA, humanMonoterpenesXIAP protein, humanX-Linked Inhibitor of Apoptosis Protein

Identifiers

PMID35572727
PMCPMC9098314
OpenAlexW4229016512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.