Evidence map›Paper›PMID 35572605›Full record

ReviewFrontiers in immunology2022

The Yin and Yang of Targeting KLRG1

Samantha M Borys, Arup K Bag, Laurent Brossay, Dennis O Adeegbe

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Reprogramming intratumoral TScience immunology · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Brain communications · 2025
    Review
  11. Article
  12. Article
  13. The role of KLRG1: a novel biomarker and new therapeutic target.Cell communication and signaling : CCS · 2024
    Review
  14. Translational Frontiers and Clinical Opportunities of Immunologically Fitted Radiotherapy.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Samantha M BorysDepartment of Molecular Microbiology and Immunology, Division of Biology and Medicine, Brown University Alpert Medical School, Providence, RI, United States.
Arup K BagDepartment of Immunology, H. Lee Moffitt Cancer Center, Tampa, FL, United States.
Laurent BrossayDepartment of Molecular Microbiology and Immunology, Division of Biology and Medicine, Brown University Alpert Medical School, Providence, RI, United States.
Dennis O AdeegbeDepartment of Immunology, H. Lee Moffitt Cancer Center, Tampa, FL, United States.
Brown University · USMoffitt Cancer Center · US

Funding

NK T Cell Interactions with NK Cells During Viral InfectionR01AI046709 · NIAID · BROWN UNIVERSITY · PI BROSSAY, LAURENT · 2001 to 2022
$8.0M
Investigating mechanistic underpinnings and therapeutic potential of selective histone deacetylase and bromodomain inhibition for the treatment of non-small cell lung cancerK22CA222669 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI ADEEGBE, DENNIS O · 2018 to 2020
$547k
NCI NIH HHS K22 CA222669NIAID NIH HHS R01 AI046709
6 · The paper itself

Abstract

The literature surrounding KLRG1 has primarily focused on NK and CD8

Indexed as

CD8-Positive T-LymphocytesT-Lymphocytes, RegulatoryAutoimmunitycancerimmune modulationKLRG1regulatory T cells (T reg)Treg targeting

Identifiers

PMID35572605
PMCPMC9098823
OpenAlexW4225107752

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.