Evidence map›Paper›PMID 35572548›Full record

ArticleFrontiers in immunology2022

CD45RB Glycosylation and Ig Isotype Define Maturation of Functionally Distinct B Cell Subsets in Human Peripheral Blood.

Jana Koers, Sabrina Pollastro, Simon Tol, Ingrid Pico-Knijnenburg, Ninotska I L Derksen, Pauline A van Schouwenburg, Mirjam van der Burg, S Marieke van Ham, Theo Rispens

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Atypical and non-classical CD45RBNature communications · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Jana KoersLandsteiner Laboratory, Sanquin Research, Department of Immunopathology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Sabrina PollastroLandsteiner Laboratory, Sanquin Research, Department of Immunopathology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Simon TolLandsteiner Laboratory, Sanquin Research, Department of Research Facilities, Amsterdam University Medical Center (UMC), University of Amsterdam, Amsterdam, Netherlands.
Ingrid Pico-KnijnenburgLaboratory for Pediatric Immunology, Department of Pediatrics, Leiden University Medical Center, Leiden, Netherlands.
Ninotska I L DerksenLandsteiner Laboratory, Sanquin Research, Department of Immunopathology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Pauline A van SchouwenburgLaboratory for Pediatric Immunology, Department of Pediatrics, Leiden University Medical Center, Leiden, Netherlands.
Mirjam van der BurgLaboratory for Pediatric Immunology, Department of Pediatrics, Leiden University Medical Center, Leiden, Netherlands.
S Marieke van HamLandsteiner Laboratory, Sanquin Research, Department of Immunopathology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Theo RispensLandsteiner Laboratory, Sanquin Research, Department of Immunopathology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.
Leiden University Medical Center · NLUniversity of Amsterdam · NLAmsterdam University Medical Centers · NLSanquin · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glycosylation of CD45RB (RB+) has recently been identified to mark antigen-experienced B cells, independent of their CD27 expression. By using a novel combination of markers including CD45RB glycosylation, CD27 and IgM/IgD isotype expression we segregated human peripheral blood B cell subsets and investigated their IGHV repertoire and

Indexed as

B-Lymphocyte SubsetsGlycosylationHumansImmunoglobulin DImmunoglobulin IsotypesImmunoglobulin MLeukocyte Common AntigensTumor Necrosis Factor Receptor Superfamily, Member 7Immunoglobulin DImmunoglobulin IsotypesImmunoglobulin MLeukocyte Common AntigensTumor Necrosis Factor Receptor Superfamily, Member 7B cell subset heterogeneityCD27CD45RB glycosylationmemory B cellsnaive B cells

Identifiers

PMID35572548
PMCPMC9095956
OpenAlexW4225015855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.