Evidence map›Paper›PMID 35572528›Full record

ArticleFrontiers in immunology2022

Propionic Acid, Induced in Gut by an Inulin Diet, Suppresses Inflammation and Ameliorates Liver Ischemia and Reperfusion Injury in Mice.

Junya Kawasoe, Yoichiro Uchida, Hiroshi Kawamoto, Tomoyuki Miyauchi, Takeshi Watanabe, Kenichi Saga, Kosuke Tanaka, Shugo Ueda, Hiroaki Terajima, Kojiro Taura and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 39 citations in OpenAlex.

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  6. AnIranian journal of basic medical sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Junya KawasoeDepartment of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yoichiro UchidaDepartment of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Hiroshi KawamotoDepartment of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Tomoyuki MiyauchiDepartment of Gastroenterological Surgery and Oncology, Kitano Hospital Medical Research Institute, Osaka, Japan.
Takeshi WatanabeDivision of Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.
Kenichi SagaDepartment of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kosuke TanakaDepartment of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Shugo UedaDepartment of Gastroenterological Surgery and Oncology, Kitano Hospital Medical Research Institute, Osaka, Japan.
Hiroaki TerajimaDepartment of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kojiro TauraDepartment of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Etsuro HatanoDepartment of Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kyoto University · JPKitano Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver ischemia and reperfusion injury (IRI) is one of the obstacles in liver surgery such as liver resection and transplantation. In this study, we investigated the preventive effect on mouse liver IRI by feeding mice with inulin, which is a heterogeneous blend of indigestible fructose polymer. Mice were fed either a control ordinary diet (CD) or an inulin diet (ID) containing 5% inulin in the CD, for 14 days before the ischemia and reperfusion (IR) maneuver. IR induced-liver damages were significantly ameliorated in the ID group, compared with those in the CD group. Feeding mice with an ID, but not a CD, elevated levels of

Indexed as

Liver DiseasesReperfusion InjuryAnimalsDietFatty Acids, VolatileInflammationInulinIschemiaMicePropionatesFatty Acids, VolatileInulinPropionatesgut microbiotainulin dietliver ischemia-reperfusion injurypropionic acidshort-chain fatty acid

Identifiers

PMID35572528
PMCPMC9097600
OpenAlexW4224295713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.