Evidence map›Paper›PMID 35571883›Full record

ArticleFrontiers in nutrition2022

Short-Term Oral Quercetin Supplementation Improves Post-exercise Insulin Sensitivity, Antioxidant Capacity and Enhances Subsequent Cycling Time to Exhaustion in Healthy Adults: A Pilot Study.

Jung-Piao Tsao, Jeffrey R Bernard, Hsiu-Chen Hsu, Chin-Lin Hsu, Su-Fen Liao, I-Shiung Cheng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 2 countries.

Jung-Piao TsaoDepartment of Sports Medicine, China Medical University, Taichung City, Taiwan.
Jeffrey R BernardDepartment of Kinesiology, California State University, Stanislaus, Turlock, CA, United States.
Hsiu-Chen HsuPhysical Education Office, Central Taiwan University of Science and Technology, Taichung City, Taiwan.
Chin-Lin HsuSchool of Nutrition, Chung Shan Medical University, Taichung City, Taiwan.
Su-Fen LiaoDepartment of Physical Medicine and Rehabilitation, Changhua Christian Hospital, Changhua City, Taiwan.
I-Shiung ChengDepartment of Physical Education, National Taichung University of Education, Taichung City, Taiwan.
California State University, Stanislaus · USCentral Taiwan University of Science and Technology · TWChina Medical University · TWChung Shan Medical University · TWNational Chung Hsing University · TWNational Taichung University of Education · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Quercetin has been reported to have antioxidant and anti-inflammatory properties on health promotion in human studies. The main purpose of this study was to investigate the effect of short-term oral quercetin supplementation on post-exercise whole-body energy metabolism. This study also aimed to determine the effects of supplementation on oxygen stress, inflammation, muscle damage, and high-intensity cycling exercise performance. Method: Twelve healthy participants, physically active students, were recruited to perform a randomized, single-blind crossover study. All subjects completed 7-days of quercetin (quercetin:1,000 mg per day for 7-days) and placebo supplementation in a randomized order. Supplement/placebo was combined with exercise consisting of 70% V̇O Results: The results showed that 7-day quercetin supplementation significantly attenuated the post-exercise glucose-induced insulin response, increased total antioxidant capacity (TAC) and superoxidase dismutase (SOD) activities, and mitigated malondialdehyde (MDA) levels during the recovery period ( Conclusion: Our findings concluded that 7-day oral quercetin supplementation enhances high-intensity cycling time to exhaustion, which may be due in part to the increase in whole-body insulin-stimulated glucose uptake and attenuation of exercise-induced oxygen stress and pro-inflammation. Therefore, quercetin may be considered an effective ergogenic aid for enhancing high-intensity cycling performance among young adults.

Indexed as

ergogenic aidsexerciseinsulin-stimulated glucose uptakequercetintime to exhaustion

Identifiers

PMID35571883
PMCPMC9096901
OpenAlexW4225014395

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.