Evidence map›Paper›PMID 35571676›Full record

ArticleNAR genomics and bioinformatics2022

Can 3D diploid genome reconstruction from unphased Hi-C data be salvaged?

Mark R Segal

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NAR genomics and bioinformatics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Advancements and future directions in single-cell Hi-C based 3D chromatin modeling.Computational and structural biotechnology journal · 2024
    Review
  3. 3D Genome Reconstruction from Partially Phased Hi-C Data.Bulletin of mathematical biology · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Mark R SegalDepartment of Epidemiology and Biostatistics, University of California, 550 16th Street, San Francisco, CA 94143-0560, USA.ORCID https://orcid.org/0000-0003-4213-3138

Funding

Reconstruction of 3D Genome Architecture from Chromatin Conformation Capture DataR01GM109457 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SEGAL, MARK R · 2013 to 2020
$2.8M
NIGMS NIH HHS R01 GM109457
6 · The paper itself

Abstract

The three-dimensional (3D) configuration of chromatin impacts numerous cellular processes. However, directly observing chromatin architecture at high resolution is challenging. Accordingly,

Identifiers

PMID35571676
PMCPMC9097817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.