ArticleTranslational cancer research2022
Does neoadjuvant chemoradiotherapy increase the effect of lateral lymph node dissection on urogenital function?
Article in Translational cancer research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 7 citations in OpenAlex.
- Feasibility and safety of lateral pelvic lymph node dissection for elderly patients with middle-low rectal cancer: results of a large multicenter lateral node collaborative group study in China.Techniques in coloproctology · 2023Article
- Lateral lymph node dissection and urogenital function with and without neoadjuvant treatment.Translational cancer research · 2022Article
- Oncological outcomes of neoadjuvant chemotherapy in patients with resectable synchronous colorectal liver metastasis: A result from a propensity score matching study.Frontiers in oncology · 2022Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: It is unclear whether neoadjuvant chemoradiotherapy (nCRT) has a deleterious influence on urogenital function in rectal cancer patients who undergone lateral lymph node dissection (LLND). The purpose of this study was to determine the incidence of urogenital dysfunction following total mesorectal excision (TME) + LLND with or without nCRT for mid-low rectal cancer, as well as to investigate the factors that predict urogenital dysfunction. Methods: From January 2015 to December 2020, a total of 106 consecutive patients who underwent TME + LLND surgery for mid-low rectal cancer were reviewed. Patients were divided into two groups based on whether they had undergone nCRT (n=51) or not (n=55). Results: Overall, 106 patients responded to the questionnaires. nCRT was not associated with urinary dysfunction [International Prostatic Symptom Score (IPSS): 9.86 Conclusions: In rectal cancer patients who had LLND, nCRT showed no significant additive effect on genitourinary function as compared to individuals who had TME + LLND alone. Urinary dysfunction was linked to the distance between the tumor and the anal margin, while age was an independent predictor of sexual dysfunction.
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