Evidence map›Paper›PMID 35571588›Full record

ArticleNano research2022

Sensitively detecting antigen of SARS-CoV-2 by NIR-II fluorescent nanoparticles.

Ruibin Hu, Tao Liao, Yan Ren, Wenming Liu, Rui Ma, Xinyuan Wang, Qihui Lin, Guoxin Wang, Yongye Liang

Open access · bronzeAbstract read
In one paragraph

Article in Nano research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. NIR-II fluorescent AgMikrochimica acta · 2023
    Article
  6. Two-Dimensional (2D) materials in the detection of SARS-CoV-2.Microchemical journal : devoted to the application of microtechniques in all branches of science · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ruibin Hu *Department of Materials Science and Engineering, Southern University of Science and Technology of China, Shenzhen, 518055 China.
Tao Liao *WWHS Biotech. Inc., Shenzhen, 518122 China.
Yan Ren *Joint Laboratory for Infectious Disease Prevention and Control, Hygienic Section of Longhua Center for Disease Control and Prevention, Longhua District, Shenzhen, 518109 China.
Wenming LiuWWHS Biotech. Inc., Shenzhen, 518122 China.
Rui MaDepartment of Materials Science and Engineering, Southern University of Science and Technology of China, Shenzhen, 518055 China.
Xinyuan WangDepartment of Materials Science and Engineering, Southern University of Science and Technology of China, Shenzhen, 518055 China.
Qihui LinJoint Laboratory for Infectious Disease Prevention and Control, Hygienic Section of Longhua Center for Disease Control and Prevention, Longhua District, Shenzhen, 518109 China.
Guoxin WangWWHS Biotech. Inc., Shenzhen, 518122 China.
Yongye LiangDepartment of Materials Science and Engineering, Southern University of Science and Technology of China, Shenzhen, 518055 China.
Southern University of Science and Technology · CNShenzhen Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is an efficient way to prevent the spread of coronavirus disease 2019 (COVID-19). Detecting SARS-CoV-2 antigen can be rapid and convenient, but it is still challenging to develop highly sensitive methods for effective diagnosis. Herein, a lateral flow assay (LFA) based on fluorescent nanoparticles emitting in the second near-infrared (NIR-II) window is developed for sensitive detection of SARS-CoV-2 antigen. Benefiting from the NIR-II fluorescence with high penetration and low autofluorescence, such NIR-II based LFA allows enhanced signal-to-background ratio, and the limit of detection is down to 0.01 ng·mL Electronic Supplementary Material: Supplementary material (the operation procedure and cost of the materials needed of NIR-II lateral flow assays, the dynamic light scattering spectrum of the NIR-II nanoparticles, the components and testing principle, optimization of main parameters pertaining to the LFA performance, the colloidal gold LFA strip, the fluorescence intensity distribution curves and the T/C values of the strips for clinical samples by NIR-II LFA, and results of clinical swab samples detected by colloidal gold LFA) is available in the online version of this article at 10.1007/s12274-022-4351-1.

Indexed as

antigen detectioncoronavirus disease 2019 (COVID-19)lateral flow assaysevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)the second near-infrared (NIR-II) fluorophores

Identifiers

PMID35571588
PMCPMC9088145
OpenAlexW4229451313

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.