Evidence map›Paper›PMID 35571321›Full record

ReviewJournal of oral and maxillofacial pathology : JOMFP

Membrane-organizing extension spike protein and its role as an emerging biomarker in oral squamous cell carcinoma.

Sushma Bommanavar, Sujata R Kanetkar, Kailas D Datkhile, Ashwini L More

Open access · greenAbstract readReview
In one paragraph

Review in Journal of oral and maxillofacial pathology : JOMFP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sushma BommanavarDepartment of Oral Pathology and Microbiology, School of Dental Sciences, KIMSDU, Karad, Maharashtra, India.
Sujata R KanetkarDepartment of Pathology, Krishna Institute of Medical Sciences, Karad, Maharashtra, India.
Kailas D DatkhileDepartment of Molecular Biology and Genetics, KIMSDU, Karad, Maharashtra, India.
Ashwini L MoreDepartment of Molecular Biology and Genetics, KIMSDU, Karad, Maharashtra, India.
Krishna Institute of Medical Sciences Deemed University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral squamous cell carcinoma (OSCC) is the most malignant tumor worldwide with a relatively poor prognosis. This can be due to lack of using new specific biomarkers as a mode of pristine interventional therapy for detecting the lesions at an early stage, thereby not allowing it to proceed to a severe advanced stage. Biomarkers, being the products of malignant cells, can prove to be promising prognostic factors in understanding the molecular pathogenesis of oral cancer. One such biomarker is membrane-organizing extension spike protein (MOESIN). Belonging to the family of ezrin/radixin/MOESIN proteins, MOESIN acts as a structural linker between plasma membrane and actin filament of the cell moiety and is involved in regulating many fundamental cellular processes such as cell morphology, adhesion and motility. This narrative review is a systematic compilation on MOESIN and its role as an emerging biomarker in OSCC.

Indexed as

Amino acid motifscytoskeleton proteinmembrane-organizing extension spike proteinmicrofilament proteinsMSN proteinoral cancer

Identifiers

PMID35571321
PMCPMC9106235
OpenAlexW4226424454

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.