ArticleJournal of oral and maxillofacial pathology : JOMFP
Comparison of blood parameters between periodontitis patients and healthy participants: A cross-sectional hematological study.
Article in Journal of oral and maxillofacial pathology : JOMFP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Periodontitis and Platelets Status: A Systematic Review With Meta-Analysis and Trial Sequential Analysis.Journal of periodontal research · 2025Pooled it
- Systematic review and meta-analysis of the association of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio with periodontitis.European journal of medical research · 2024Pooled it
- Relationship between dietary diversity and periodontitis: analysis of NHANES 2003-2014.Acta odontologica Scandinavica · 2026Article
- The effect of Stage I-II periodontitis on the mechanical, structural, and biological properties of leukocyte and platelet-rich fibrin.Journal of applied oral science : revista FOB · 2026Article
- Associations between periodontitis and postoperative infectious complications in OSCC patients: a retrospective study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Can Preoperative Blood Inflammatory Biomarkers Predict Early Dental Implant Outcomes in Systemically Healthy Patients?Bioengineering (Basel, Switzerland) · 2025Article
- Anaemia and Other Haemogram Parameters Associated With Benign Maxillomandibular Odontogenic Lesions.Advances in hematology · 2025Article
- Predictive Value of Complete Blood Count Parameters for Alzheimer's Disease in Relation to Periodontal Status.Current Alzheimer research · 2025Article
- The Association Between Periodontal Inflamed Surface Area (PISA), Inflammatory Biomarkers, and Mitochondrial DNA Copy Number.Journal of clinical medicine · 2024Article
- Inflammation indices in association with periodontitis and cancer.Periodontology 2000 · 2024Review
- Association between high-density lipoprotein-related inflammation index and periodontitis: insights from NHANES 2009-2014.Lipids in health and disease · 2024Article
- The Bloody Crossroads: Interactions between Periodontitis and Hematologic Diseases.International journal of molecular sciences · 2024Review
- Assessment of the Effect on Periodontitis of Antibiotic Therapy and Bacterial Lysate Treatment.International journal of molecular sciences · 2024Article
- Mean platelet volume is associated with periodontitis: a cross-sectional study.BMC oral health · 2024Article
- Are Adults Over 18 Years of Age with Anaemia More Likely to Develop Chronic Periodontitis Than Adults Without Anaemia? - A Systematic Review and Meta-Analysis.Journal of International Society of Preventive & Community DentistryReview
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Bacteria and their products involved in periodontitis evoke an immunoinflammatory response in the host tissue. Inflammatory diseases, such as periodontitis, are often not just a local event, but may have systemic ramifications, including elevations in the numbers of circulating leukocytes, acute-phase proteins and oxidative stress markers. It is now emerging that also erythrocytes are affected by chronic inflammatory diseases. This phenomenon, named "anemia of inflammation," is not caused by marrow deficiencies or other diseases. The present study aimed to assess whether there was any relation between chronic periodontitis and hematological parameters. Materials and Methods: A total of 80 patients were included in the study and were divided into the healthy and periodontitis groups. Blood sample was obtained from each participant for hematological analysis of leukocytes, erythrocytes, platelets, red blood cell (RBC) distribution width (RDW), mean corpuscular volume (MCV), platelet count and neutrophil-leukocyte ratio (NLR). Further, the values were gathered and subjected to statistical analysis. Unpaired Results: Results show statistically significant difference seen in leukocytes, lymphocytes, RDW, MCV, platelet count and NLR which was higher in patients with periodontitis, all other parameters are nonsignificant. Conclusion: Thus, within limitations, it can be concluded that increased levels of leukocytes, lymphocytes, RDW, MCV, platelet count and NLR depict the inflammatory state and destructive nature of periodontitis.
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