Evidence map›Paper›PMID 35571170›Full record

ReviewFrontiers in cardiovascular medicine2022

The Long-Term Outcomes of Ablation With Vein of Marshall Ethanol Infusion vs. Ablation Alone in Patients With Atrial Fibrillation: A Meta-Analysis.

Feng Li, Jin-Yu Sun, Li-Da Wu, Lei Zhang, Qiang Qu, Chao Wang, Ling-Ling Qian, Ru-Xing Wang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 5 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 5 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Ethanol infusion of the vein of marshall-based strategies for persistent atrial fibrillation: a systematic review and meta-analysis of randomized trials.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Pooled it
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  6. Review
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  8. International Survey on Vein of Marshall Retrograde Ethanol Infusion.Circulation. Arrhythmia and electrophysiology · 2025
    Article
  9. Tips and Tricks to Perform a Successful Vein of Marshall Alcohol Ablation.The Journal of innovations in cardiac rhythm management · 2025
    Review
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  11. Article
  12. Evaluation of posterior mitral isthmus ablation in the absence of a vein of Marshall.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Feng LiDepartment of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Jin-Yu SunDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Li-Da WuDepartment of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Lei ZhangDepartment of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Qiang QuDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Chao WangDepartment of Cardiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Ling-Ling QianDepartment of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Ru-Xing WangDepartment of Cardiology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Nanjing Medical University · CNJiangsu Province Hospital · CNWuxi People's Hospital · CNFirst Affiliated Hospital of GuangXi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The long-term outcomes of ablation with vein of Marshall ethanol infusion (VOM-ABL) compared with ablation alone in patients with atrial fibrillation (AF) remains elusive. We aimed to explore whether VOM-ABL showed better long-term benefits and screen the potential determinants of outcome impact of VOM-ABL procedure. Methods: PubMed, Cochrane Library, Web of Science, and Embase were searched up to 1st September 2021. Studies comparing the long-term (one-year or longer) outcomes between VOM-ABL and ablation alone were included. Subgroup analysis identified potential determinants for VOM-ABL procedure. Results: Compared with ablation alone, VOM-ABL was associated with a significantly higher rate of long-term freedom from AF/AT (risk ratio [RR], 1.28; 95% confidence interval [CI], 1.12-1.47; Conclusions: This meta-analysis demonstrates that VOM-ABL has superior efficacy and comparable safety over ablation alone in AF patients with long-term follow-up. Moreover, PVI+ and VOM-ABL group sample size ≥ 100 may be associated with a great impact on freedom from AF/AT and MI block, respectively.

Indexed as

ablationatrial fibrillationethanol effusionmeta-analysisvein of Marshall

Identifiers

PMID35571170
PMCPMC9098965
OpenAlexW4225146355

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.