Evidence map›Paper›PMID 35571023›Full record

ArticleFrontiers in genetics2022

A View on Genomic Medicine Activities in Africa: Implications for Policy.

C Victor Jongeneel, Maritha J Kotze, Archana Bhaw-Luximon, Faisal M Fadlelmola, Yasmina J Fakim, Yosr Hamdi, Samar Kamal Kassim, Judit Kumuthini, Victoria Nembaware, Fouzia Radouani and 2 more

Abstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

C Victor JongeneelIndependent Consultant, Rolle, Switzerland.
Maritha J KotzeDivision of Chemical Pathology, Department of Pathology, Faculty of Medicine and Health Sciences, Stellenbosch University and National Health Laboratory Service, Tygerberg Hospital, Cape Town, South Africa.
Archana Bhaw-LuximonCenter for Biomedical and Biomaterials Research, University of Mauritius, Reduit, Mauritius.
Faisal M FadlelmolaCentre for Bioinformatics and Systems Biology, Faculty of Science, University of Khartoum, Khartoum, Sudan.
Yasmina J FakimBiotechnology Unit, Faculty of Agriculture, University of Mauritius, Reduit, Mauritius.
Yosr HamdiLaboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de Tunis, Universite' Tunis El Manar, Tunis, Tunisia.
Samar Kamal KassimMedical Biochemistry and Molecular Biology Department, Faculty of Medicine, Ain Shams University and MASRI Research Institute, Ain Shams University, Cairo, Egypt.
Judit KumuthiniSouth African National Bioinformatics Institute (SANBI), Life Sciences Building, University of Western Cape (UWC), Cape Town, South Africa.
Victoria NembawareDivision of Human Genetics, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Fouzia RadouaniChlamydiae and Mycoplasmas Laboratory, Research Department, Institut Pasteur du Maroc, Casablanca, Morocco.
Nicki TiffinComputational Biology Division, Department of Integrative Biomedical Sciences, IDM, University of Cape Town Faculty of Health Sciences, Cape Town, South Africa.
Nicola MulderComputational Biology Division, Department of Integrative Biomedical Sciences, IDM, University of Cape Town Faculty of Health Sciences, Cape Town, South Africa.

Funding

Medical Research Council MC_PC_MR/T037733/1
6 · The paper itself

Abstract

Genomics policy development involves assessing a wide range of issues extending from specimen collection and data sharing to whether and how to utilize advanced technologies in clinical practice and public health initiatives. A survey was conducted among African scientists and stakeholders with an interest in genomic medicine, seeking to evaluate: 1) Their knowledge and understanding of the field. 2) The institutional environment and infrastructure available to them. 3) The state and awareness of the field in their country. 4) Their perception of potential barriers to implementation of precision medicine. We discuss how the information gathered in the survey could instruct the policies of African institutions seeking to implement precision, and more specifically, genomic medicine approaches in their health care systems in the following areas: 1) Prioritization of infrastructures. 2) Need for translational research. 3) Information dissemination to potential users. 4) Training programs for specialized personnel. 5) Engaging political stakeholders and the public. A checklist with key requirements to assess readiness for implementation of genomic medicine programs is provided to guide the process from scientific discovery to clinical application.

Indexed as

Africacapacity developmentgenomic medicineinfrastructurePathology-supported genomicsprecision medicine stakeholdersreadiness checklisttranslational research

Identifiers

PMID35571023
PMCPMC9091728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.