Evidence map›Paper›PMID 35571008›Full record

ArticleBurns open : an international open access journal for burn injuries2022

Wound healing in older adults with severe burns: Clinical treatment considerations and challenges.

Kathleen S Romanowski, Soman Sen

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Burns open : an international open access journal for burn injuries, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07526610 (Predictive Mortality Scales in the Burn Patient Admitted to the Intensive Care Unit), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07526610 completednot on this map

Predictive Mortality Scales in the Burn Patient Admitted to the Intensive Care Unit

TypeobservationalSponsorUniversidad Rey Juan CarlosRan2019 to 2026Enrolled465ConditionsBurn Any Degree Involving 20-29 Percent of Body Surface, Burn Any Degree Involving 30-39 Percent of Body Surface, Burn Any Degree Involving 40-49 Percent of Body Surface, Burn Any Degree Involving 50-59 Percent of Body Surface
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. [Clinical efficacy of human biological dressing transplantation for refractory wounds in middle-aged and elderly patients].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025
    Observational
  7. Article
  8. Article
  9. Article
  10. Review
  11. State and Future Science of Opioids and Potential of Biased-ligand Technology in the Management of Acute Pain After Burn Injury.Journal of burn care & research : official publication of the American Burn Association · 2023
    Review
  12. Article
  13. Article
  14. Comparative Analysis of Composite Mortality Prediction Scores in Intensive Care Burn Patients.International journal of environmental research and public health · 2022
    Article
  15. Microneedle-Mediated Delivery of Extracellular Matrix-Inspired Peptides for Mitigation of Burn Wound Progression and Support of Tissue Repair.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Kathleen S RomanowskiDepartment of Surgery, University of California, Davis, 2335 Stockton Blvd., Sacramento, CA 95817, USA.
Soman SenDepartment of Surgery, University of California, Davis, 2335 Stockton Blvd., Sacramento, CA 95817, USA.
Shriners Hospitals for Children - Northern California · USUniversity of California, Davis · US

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
NCATS NIH HHS UL1 TR001860
6 · The paper itself

Abstract

Background: The older adult population continues to rapidly expand in number, with a projection by the United States (US) Census Bureau that there will be more individuals older than > 65 years (77.0 million) than those younger than < 18 years (76.5 million) by 2034. This review provides an overview of aging as it relates to wound healing and burn injuries in older adult patients, summarizes current treatment practices, and addresses the key challenges and considerations for treating severe burn injuries in this specific patient population. Materials and methods: A narrative literature search was conducted, focusing on recent primary literature on burns and wound healing in elderly patients. Results: Studies showed that the aging process results in both physiologic (eg, nutritional and metabolic status) and anatomic changes (eg, thinning dermis) that contribute to a reduced capacity to recover from burn-injury trauma compared with younger patients. Owing to impaired vision, decreased coordination, comorbidities, and medication-induced side effects, older adults (ie, > 65 years) are susceptible to severe burn injury (deep-partial thickness and full-thickness), which is associated with significant morbidity and mortality. Conclusion: A better understanding of the effects of age-related changes regarding wound healing in older adult patients who incur severe burn injuries may provide insight into clinical strategies to improve outcomes among this population.

Indexed as

AgingBurnsBurn treatmentGeriatricOlder adultWound healing

Identifiers

PMID35571008
PMCPMC9104500
OpenAlexW4210344205

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.