Evidence map›Paper›PMID 35571001›Full record

ArticleKidney international reports2022

Incremental and Personalized Hemodialysis Start: A New Standard of Care.

Massimo Torreggiani, Antioco Fois, Antoine Chatrenet, Louise Nielsen, Lurlynis Gendrot, Elisa Longhitano, Léna Lecointre, Claudine Garcia, Conrad Breuer, Béatrice Mazé and 6 more

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Impact of incremental initiation of haemodialysis on mortality: a systematic review and meta-analysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023
    Pooled it
  3. Trial
  4. Observational
  5. Ten tips for the first hemodialysis sessions.Clinical kidney journal · 2026
    Review
  6. Article
  7. Review
  8. Review
  9. A website calculator to benchmark the carbon footprint of haemodialysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Article
  10. Article
  11. Review
  12. Observational
  13. Green, Sustainable Nephrology: State of the Art Needs for Education and Implementation.Clinical journal of the American Society of Nephrology : CJASN · 2025
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Twice Weekly versus Thrice Weekly Hemodialysis-A Pilot Cross-Over Equivalence Trial.Clinical journal of the American Society of Nephrology : CJASN · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Massimo TorreggianiNephrology and Dialysis, Centre Hospitalier Le Mans, Le Mans, France.
Antioco FoisNephrology and Dialysis, Centre Hospitalier Le Mans, Le Mans, France.
Antoine ChatrenetNephrology and Dialysis, Centre Hospitalier Le Mans, Le Mans, France.
Louise NielsenNephrology and Dialysis, Centre Hospitalier Le Mans, Le Mans, France.
Lurlynis GendrotNephrology and Dialysis, Centre Hospitalier Le Mans, Le Mans, France.
Elisa LonghitanoNephrology and Dialysis, Centre Hospitalier Le Mans, Le Mans, France.
Léna LecointreCentre Hospitalier Le Mans, Le Mans, France.
Claudine GarciaNephrology and Dialysis, Centre Hospitalier Le Mans, Le Mans, France.
Conrad BreuerCentre Hospitalier Le Mans, Le Mans, France.
Béatrice MazéNephrology and Dialysis, Centre Hospitalier Le Mans, Le Mans, France.
Assia HamiInstitut de Néphrologie Immuno-Transplantation, Hôpital Hôtel Dieu, Centre Hospitalier Universitaire de Nantes, Nantes, France.
Guillaume SeretCentre ECHO, Pôle Santé Sud, Le Mans, France.
Patrick SaulniersDépartement de Biostatistiques et Méthodologie, Centre Hospitalier Universitaire d'Angers, Angers, France.
Pierre RoncoNephrology and Dialysis, Centre Hospitalier Le Mans, Le Mans, France.
Frederic LavainneAssociation ECHO, Pôle Santé Atlantique, Saint-Herblain, France.
Giorgina Barbara PiccoliNephrology and Dialysis, Centre Hospitalier Le Mans, Le Mans, France.
Centre Hospitalier du Mans · FRADIR Association · FRCentre Hospitalier Universitaire d'Angers · FRCentre Hospitalier Universitaire de Nantes · FRInserm · FRLe Mans Université · FRUniversity of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Incremental hemodialysis (iHD) may attenuate "dialysis shock" and reduce costs, preserving quality of life. It is considered difficult to reconcile with HD wards' routine; fear of underdialysis and increasing mortality are additional concerns. The aim of this study was to evaluate mortality, morbidity, and costs in a large HD ward where iHD is the standard of HD start. Methods: This observational study included all incident HD patients in 2017 to 2021, stratified according to HD start: iHD (1-2 sessions/wk), decremental HD (dHD, 3 sessions/wk at start, later reduced), or standard (3 sessions/wk). Results were compared with data recorded in the same unit before the incremental program (2015-2017) and with a propensity score-matched cohort from the French Renal Epidemiology and Information Network (REIN) registry. Results: A total of 158 patients started HD in 2017 to 2021, 57.6% on iHD, 8.9% dHD, and 33.5% standard HD schedule. Patients on the standard schedule had lower initial estimated glomerular filtration rate (eGFR) (5 vs. 7 ml/min per 1.72 m Conclusion: Our study reveals that iHD can be a new standard of care, as it is safe and feasible in up to two-thirds of patients on incident HD.

Indexed as

cost analysisincremental hemodialysispersonalized hemodialysispredialysis carepropensity score matchingsurvival

Identifiers

PMID35571001
PMCPMC9091804
OpenAlexW4213143256

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.