Evidence map›Paper›PMID 35570748›Full record

ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2022

Treatment of coronary bifurcation lesions, part I: implanting the first stent in the provisional pathway. The 16th expert consensus document of the European Bifurcation Club.

Remo Albiero, Francesco Burzotta, Jens Flensted Lassen, Thierry Lefèvre, Adrian P Banning, Yiannis S Chatzizisis, Thomas W Johnson, Miroslaw Ferenc, Manuel Pan, Olivier Daremont and 4 more

Registry-linked trialOpen access · greenAbstract readConsensus Statement
In one paragraph

Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06822322 (The European Bifurcation Club Randomized Trial of Stepwise Provisional Stenting Versus Drug Coated Balloon Therapy for Non-left Main True Coronary Bifurcations - EBC DCB Study), which is not on this map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
21.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06822322 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

The European Bifurcation Club Randomized Trial of Stepwise Provisional Stenting Versus Drug Coated Balloon Therapy for Non-left Main True Coronary Bifurcations - EBC DCB Study

TypeinterventionalSponsorCeric SàrlRan2025 to 2035Enrolled750ConditionsCoronary Artery Disease (non-left Main), Coronary Bifurcation LesionArmsPercutaneous Coronary Angioplasty, Stepwise Provisional Stent Strategy, Drug Coated Balloon Strategy, Cross-Over Stepwise Provisional Stent Strategy
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 107 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. PCI for Ostial Stenosis of Left Circumflex or Left Anterior Descending Artery.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Observational
  5. Article
  6. Article
  7. Observational
  8. Article
  9. A Comparison of a Drug Coated Balloon With Drug Eluting Stent Strategy for Treating Coronary Bifurcation Lesions.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
  10. Article
  11. Review
  12. Review
  13. Coronary Bifurcation PCI-Part II: Advanced Considerations.Journal of cardiovascular development and disease · 2025
    Review
  14. Coronary Bifurcation PCI-Part I: Fundamentals.Journal of cardiovascular development and disease · 2025
    Review
  15. Article
  16. Observational
  17. Identifying Unintended Stent Deformations in Aorto-Ostial Left Main Percutaneous Coronary Interventions.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Article
  18. Article
  19. Article
  20. Double-Kissing Crush Versus Provisional Stenting for Coronary Bifurcations: A 1-Year Follow-up Study in Vietnam.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 12 institutions in 8 countries.

Remo AlbieroInterventional Cardiology Unit, Ospedale Civile di Sondrio, Sondrio, Italy.
Francesco BurzottaInstitute of Cardiology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Jens Flensted LassenDepartment of Cardiology B, Odense Universitates Hospital & University of Southern Denmark, Odense C, Denmark.
Thierry LefèvreInstitut Cardiovasculaire Paris Sud, Hôpital Privé Jacques Cartier, Ramsay Santé, Massy, France.
Adrian P BanningCardiovascular Medicine Division, Radcliffe Department of Medicine, John Radcliffe Hospital, Oxford, United Kingdom.
Yiannis S ChatzizisisCardiovascular Division, University of Nebraska Medical Center, Omaha, NE, USA.
Thomas W JohnsonDepartment of Cardiology, Bristol Heart Institute, University Hospitals Bristol and Weston NHSFT & University of Bristol, Bristol, United Kingdom.
Miroslaw FerencDivision of Cardiology and Angiology II, University Heart Center Freiburg-Bad Krozingen, Bad Krozingen, Germany.
Manuel PanDepartment of Cardiology, Reina Sofia Hospital. University of Cordoba (IMIBIC), Cordoba, Spain.
Olivier DaremontClinique St Augustin, Bordeaux, France.
David Hildick-SmithSussex Cardiac Centre, Royal Sussex County Hospital, Brighton and Sussex University Hospitals, Brighton, United Kingdom.
Alaide ChieffoInterventional Cardiology Unit, San Raffaele Scientific Institute, Milan, Italy.
Yves LouvardInstitut Cardiovasculaire Paris Sud, Hôpital Privé Jacques Cartier, Ramsay Santé, Massy, France.
Goran StankovicDepartment of Cardiology, Clinical Center of Serbia, and Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Hôpital Privé Jacques Cartier · FRAzienda Ospedaliera di Valtellina e Valchiavenna · ITInstituto Maimónides de Investigación Biomédica de Córdoba · ESJohn Radcliffe Hospital · GBSan Raffaele University of Rome · ITSussex County Community College · USUniversità Cattolica del Sacro Cuore · ITUniversitäts-Herzzentrum Freiburg-Bad Krozingen · DEUniversity of Belgrade · RSUniversity of Bristol · GBUniversity of Nebraska Medical Center · USUniversity of Southern Denmark · DK

Funding

Patient-Specific Simulations to Guide Coronary Bifurcation StentingR01HL144690 · NHLBI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI CHATZIZISIS, IOANNIS S · 2019 to 2023
$3.9M
NHLBI NIH HHS R01 HL144690
6 · The paper itself

Abstract

Stepwise layered provisional stenting (PS) is the most commonly used strategy to treat coronary bifurcation lesions (CBL). The term 'stepwise layered' emphasises the versatility of this approach that allows the adjustment of the procedure plan according to the CBL complexity, starting with stent implantation in one branch and implantation of a second stent in the other branch only when required. A series of refinements have been implemented over the years to facilitate the achievement of predictable procedural results using this approach. However, despite its simplicity and versatility, operators using this technique require full knowledge of the pitfalls of each procedural step. Part I of this 16

Indexed as

Angioplasty, Balloon, CoronaryCoronary Artery DiseaseConsensusCoronary AngiographyHumansStentsTime FactorsTreatment Outcome

Identifiers

PMID35570748
PMCPMC10259243
OpenAlexW4280601584

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.