Evidence map›Paper›PMID 35570679›Full record

ReviewQuarterly reviews of biophysics2022

Digging into the biophysical features of cell membranes with lipid-DNA conjugates.

Ahsan Ausaf Ali, Yousef Bagheri, Mingxu You

Open access · hybridAbstract readReview
In one paragraph

Review in Quarterly reviews of biophysics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. DNA-modulated dimerization and oligomerization of cell membrane receptors.Chemical communications (Cambridge, England) · 2024
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ahsan Ausaf AliDepartment of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003, USA.
Yousef BagheriDepartment of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003, USA.
Mingxu YouDepartment of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003, USA.ORCID 0000-0002-5279-2340
University of Massachusetts Amherst · US

Funding

Defining Mechanical Landscapes at Cell-Cell JunctionsR35GM133507 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Mingxu You · 2019 to 2026
$2.8M
NIGMS NIH HHS R35 GM133507
6 · The paper itself

Abstract

Lipid-DNA conjugates have emerged as highly useful tools to modify the cell membranes. These conjugates generally consist of a lipid anchor for membrane modification and a functional DNA nanostructure for membrane analysis or regulation. There are several unique properties of these lipid-DNA conjugates, especially including their programmability, fast and efficient membrane insertion, and precise sequence-specific assembly. These unique properties have enabled a broad range of biophysical applications on live cell membranes. In this review, we will mainly focus on recent tremendous progress, especially during the past three years, in regulating the biophysical features of these lipid-DNA conjugates and their key applications in studying cell membrane biophysics. Some insights into the current challenges and future directions of this interdisciplinary field have also been provided.

Indexed as

DNANanostructuresBiophysicsCell MembraneLipidsDNALipidsCell membrane modificationDNA probesintercellular interactionslipid-DNA conjugatemembrane biophysicsmembrane channelsmembrane signaling

Identifiers

PMID35570679
PMCPMC9284422
OpenAlexW4280503641

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.