ArticleJournal of applied clinical medical physics2022
Characterization of imaging performance of a novel helical kVCT for use in image-guided and adaptive radiotherapy.
Article in Journal of applied clinical medical physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Performance of a Vendor System for Systematic Offline Adaptive Breast Helical Radiotherapy.Cancers · 2026Article
- Imaging dose and image quality of kilovoltage imaging implemented on a helical tomotherapy unit.Zeitschrift fur medizinische Physik · 2026Article
- Feasibility of reusing online-generated treatment plans for adaptive radiotherapy in prostate cancer.Physics and imaging in radiation oncology · 2026Article
- Feasibility and workflow efficiency of automated deep inspiration breath-hold for locoregional breast irradiation on a ring-gantry accelerator.Physics and imaging in radiation oncology · 2026Article
- Dosimetric evaluation of synthetic kilo-voltage CT images generated from megavoltage CT for head and neck tomotherapy using a conditional GAN network.Physical and engineering sciences in medicine · 2025Article
- Correlation between exposure (mAs) and image quality for a rapid cone-beam CT on a ring gantry linear accelerator.Journal of applied clinical medical physics · 2025Article
- Comparative evaluation of image-guided radiation therapy (IGRT)-based dose calculation accuracy using cone-beam, megavoltage, and kilovoltage CT modalities.Journal of applied clinical medical physics · 2025Article
- Inter-institutional variability in CT-to-mass-density conversion tables for helical tomotherapy: a national survey in Japan.Journal of radiation research · 2025Article
- Comparative analysis of kVCT- and MVCT-guided helical tomotherapy for total body irradiation: evaluation of process times and residual setup errors.Journal of radiation research · 2025Article
- Evaluating dosimetric outcomes: a comparison of CyberKnife, VMAT FFF, and Helical Tomotherapy Radixact for treating localized prostate cancer.La Radiologia medica · 2025Article
- Multi-institutional study on image quality for a novel CBCT solution on O-ring linac.Journal of applied clinical medical physics · 2025Article
- Verification of daily dose recalculation accuracy for an adaptive radiation therapy monitoring tool in helical tomotherapy for nasopharyngeal carcinoma.Journal of applied clinical medical physics · 2025Article
- Tomotherapy megavoltage computed tomography for lung tumor positioning and contouring.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025Article
- Adaptive radiotherapy in locally advanced head and neck cancer: The importance of reduced margins.Physics and imaging in radiation oncology · 2025Article
- Evaluation of superficial tumor treatment using radixact with the kilovoltage computed tomography system: dosimetric and clinical feasibility of super stuff bolus.Frontiers in oncology · 2025Article
- Article
- A novel comprehensive metric balancing imaging dose and setup accuracy in image-guided radiotherapy: concept proposal and clinical validation.Frontiers in oncology · 2024Article
- Impact of delivery time factor on treatment time and plan quality in tomotherapy.Scientific reports · 2023Article
- Influence of different air CT numbers for IVDT on the dose distribution in TomoTherapy MVCT.Journal of applied clinical medical physics · 2023Article
- Article
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5 authors.
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Abstract
ClearRT helical kVCT imaging for the Radixact helical tomotherapy system recently received FDA approval and is available for clinical use. The system is intended to enhance image fidelity in radiation therapy treatment planning and delivery compared to the prior MV-based onboard imaging approach. The purpose of this work was to characterize the imaging performance of this system and compare this performance with that of clinical systems used in image-guided and/or adaptive radiotherapy (ART) or computed tomography (CT) simulation, including Radixact MVCT, TomoTherapy MVCT, Varian TrueBeam kV OBI CBCT, and the Siemens SOMATOM Definition Edge kVCT. A CT image quality phantom was scanned across clinically relevant acquisition modes for each system to evaluate image quality metrics, including noise, uniformity, contrast, spatial resolution, and CT number linearity. Similar noise levels were observed for ClearRT and Siemens Edge, whereas noise for the other systems was ∼1.5-5 times higher. Uniformity was best for Siemens Edge, whereas most scans for ClearRT exhibited a slight "cupping" or "capping" artifact. The ClearRT and Siemens Edge performed best for contrast metrics, which included low-contrast visibility and contrast-to-noise ratio evaluations. Spatial resolution was best for TrueBeam and Siemens Edge, whereas the three kVCT systems exhibited similar CT number linearity. Overall, these results provide an initial indication that ClearRT image quality is adequate for image guidance in radiotherapy and sufficient for delineating anatomic structures, thus enabling its use for ART. ClearRT also showed significant improvement over MVCT, which was previously the only onboard imaging modality available on Radixact. Although the acquisition of these scans does come at the cost of additional patient dose, reported CTDI values indicate a similar or generally reduced machine output for ClearRT compared to the other systems while maintaining comparable or improved image quality overall.
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