ArticleBMC gastroenterology2022
Oncologic outcome of colon cancer with perforation and obstruction.
Article in BMC gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Inadvertent laparoscopic lavage of perforated colon cancer: a systematic review.Langenbeck's archives of surgery · 2024Pooled it
- Emergency Diagnostic Phenotypes and Differential Survival in Colorectal Cancer: A Real-World Cohort Study.Diagnostics (Basel, Switzerland) · 2026Article
- Colonic Stenting as a Bridge to Surgery Versus Emergency Resection in Obstructive Colon Cancer: A Systematic Review of Surgical Outcomes.Journal of clinical medicine · 2026Review
- First Successful Regeneration of a Structurally Native-Like Colon Using a Bioabsorbable Polymer Sheet.Annals of gastroenterological surgery · 2026Article
- Independent Prognostic Significance of Perforation in Colorectal Cancer: Insights From a Propensity Score-Matched Cohort Study.Annals of gastroenterological surgery · 2026Article
- Clinical profile, treatment patterns, and early outcomes of colorectal cancer at Kassala Police Hospital, Eastern Sudan: a 10-year retrospective cohort study.Scientific reports · 2026Article
- Multitask radioclinical decision stratification in non-metastatic colon cancer: integrating MMR status, pT staging, and high-risk pathological factors.Abdominal radiology (New York) · 2026Article
- Emerging role of low-frequency somatic mutations in cancer relapse: from early detection to precision oncology.Frontiers in oncology · 2026Review
- Clinical Characteristics and Outcomes of Oncologic Surgical Emergencies: A Retrospective Study.Annals of surgical oncology · 2025Article
- Local and National Trends in Emergency Presentation of Colon and Rectal Cancer.Journal of surgical oncology · 2025Article
- Clinical effect and prognosis of laparoscopic surgery on colon cancer complicated with intestinal obstruction patients.World journal of gastrointestinal surgery · 2025Article
- Prognostic determinants in surgical critial patients undergoing emergency surgery for Stage III or higher colorectal cancer.Langenbeck's archives of surgery · 2025Article
- The Clinical Characteristics of a Stage II Colorectal Cancer T4 Tumor: A Ten-Year Single-Center Research Report.Current oncology (Toronto, Ont.) · 2024Article
- Comparison of postoperative prognoses for resectable colorectal cancer with vs. without oncologic emergency using propensity score‑matched analyses: A single-center retrospective observational study.Oncology letters · 2024Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePerforation and obstruction in colorectal cancer are poor prognostic factors. We aimed to evaluate the oncological outcomes of patients with colon cancer presenting with perforation or obstruction.
methodsA total of 260 patients underwent surgery for colon cancer between January 2015 and December 2017. Among them, 54 patients who underwent emergency surgery for perforated (n = 32) or obstructive (n = 22) colon cancer were included.
resultsThe perforation (PG, n = 32) and obstruction groups (OG, n = 22) did not differ significantly in age (p = 0.486), sex (p = 0.821), tumor stage (p = 0.221), tumor location (p = 0.895), histologic grade (p = 0.173), or 3-year overall survival rate (55.6% vs. 50.0%, p = 0.784). However, the PG had a higher postoperative complication rate (44% vs. 17%, p = 0.025), longer intensive care unit stay (4.8 days vs. 0.8 days, p = 0.047), and lower 3-year recurrence-free survival (42.4% vs. 78.8%, p = 0.025) than the OG. In the multivariate analysis, perforation was significantly increased risk of recurrence (hazard ratio = 3.67, 95% confidence interval: 1.049-12.839, p = 0.042).
conclusionPatients with colon cancer initially presenting with perforation had poorer recurrence-free survival, higher postoperative complication rates, and longer ICU stays than those who had obstruction.
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