Evidence map›Paper›PMID 35570022›Full record

ReviewThe Journal of thoracic and cardiovascular surgery2024

Incidence, characteristics, and outcomes of reintervention after mitral transcatheter edge-to-edge repair.

Tsuyoshi Kaneko, Paige C Newell, Sarah Nisivaco, Sang Gune K Yoo, Sameer A Hirji, Hechuan Hou, Matthew Romano, D Scott Lim, Stan Chetcuti, Pinak Shah and 2 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Journal of thoracic and cardiovascular surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Tsuyoshi KanekoDivisions of Cardiac Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass. Electronic address: tkaneko2@bwh.harvard.edu.
Paige C NewellDivisions of Cardiac Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.
Sarah NisivacoDivisions of Cardiac Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.
Sang Gune K YooDepartment of Internal Medicine, Michigan Medicine, Ann Arbor, Mich.
Sameer A HirjiDivisions of Cardiac Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.
Hechuan HouDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.
Matthew RomanoDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.
D Scott LimDivision of Cardiovascular Medicine, University of Virginia Health System, Charlottesville, Va.
Stan ChetcutiDepartment of Cardiovascular Medicine, Michigan Medicine, Ann Arbor, Mich.
Pinak ShahDivision of Cardiology, Brigham and Women's Hospital, Boston, Mass.
Gorav AilawadiDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.
Michael ThompsonDepartment of Cardiac Surgery, Michigan Medicine, Ann Arbor, Mich.

Funding

Determinants, Outcomes, and Financial Incentives Associated with Cardiac Rehabilitation Enrollment After Cardiac SurgeryK01HS027830 · AHRQ · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI THOMPSON, MICHAEL PATRICK · 2021 to 2025
$711k
AHRQ HHS K01 HS027830
6 · The paper itself

Abstract

objectiveThe use of transcatheter edge-to-edge repair (TEER) is growing substantially, and reintervention after TEER by way of repeat TEER or mitral valve surgery (MVS) is increasing as a result. In this nationally representative study we examined the incidence, characteristics, and outcomes of reintervention after index TEER.

methodsBetween July 2013 and November 2017, we reviewed 11,396 patients who underwent index TEER using Medicare beneficiary data. These patients were prospectively tracked and identified as having repeat TEER or MVS. Primary outcomes included 30-day mortality, 30-day readmission, 30-day composite morbidity, and cumulative survival.

resultsAmong 11,396 patients who underwent TEER, 548 patients (4.8%) required reintervention after a median time interval of 4.5 months. Overall 30-day mortality was 8.6%, 30-day readmission was 20.9%, and 30-day composite morbidity was 48.2%. According to reintervention type, 294 (53.7%) patients underwent repeat TEER, and 254 (46.3%) underwent MVS. Patients who underwent MVS were more likely to be younger and female, but had a similar comorbidity burden compared with the repeat TEER cohort. After adjustment, there were no differences in 30-day mortality (adjusted odds ratio [AOR], 1.26 [95% CI, 0.65-2.45]) or 30-day readmission (AOR, 1.14 [95% CI, 0.72-1.81]). MVS was associated with higher 30-day morbidity (AOR, 4.76 [95% CI, 3.17-7.14]) compared with repeat TEER. Requirement for reintervention was an independent risk factor for long-term mortality in a Cox proportional hazard model (hazard ratio, 3.26 [95% CI, 2.53-4.20]).

conclusionsReintervention after index TEER is a high-risk procedure that carries a significant mortality burden. This highlights the importance of ensuring procedural success for index TEER to avoid the morbidity of reintervention altogether.

Indexed as

Heart Valve Prosthesis ImplantationMitral Valve InsufficiencyAgedFemaleHumansIncidenceMedicareOdds RatioPatient ReadmissionRisk FactorsTreatment OutcomeUnited Statesmitral regurgitationmitral valvemitral valve surgeryreinterventiontranscatheter edge-to-edge repair

Identifiers

PMID35570022
PMCPMC12666776

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.