ArticleInternational dental journal2022
Fluoride Delivered via a Topical Application of 38% SDF and 5% NaF.
Article in International dental journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 22 citations in OpenAlex.
- Randomized Clinical Trial on Caries Prevention of Silver Diamine Fluoride.Journal of dental research · 2026Trial
- Plaque and Salivary Fluoride Levels in Preschoolers Following Applications of Silver Diamine Fluoride, Sodium Fluoride Varnish, and Their Combination: A Randomized Clinical Trial.International journal of paediatric dentistry · 2026Trial
- A Randomized Controlled Trial of Silver Diamine Fluoride Application Time.Journal of dental research · 2025Trial
- Caries Prevention Using Silver Diamine Fluoride: A 12-Month Clinical Trial.International dental journal · 2023Trial
- Influence of Time Interval, Temperature, and Storage Condition on Fluoride Release and Recharge from Silorane-Based Restorative Materials.Dentistry journal · 2025Article
- Remineralizing effect of NSF on artificial enamel caries.BMC oral health · 2024Article
- Ion Concentration of Silver Diamine Fluoride Solutions.International dental journal · 2022Article
- Silver diamine fluoride therapy for dental care.The Japanese dental science review · 2022Review
- A Review of the Protocol of SDF Therapy for Arresting Caries.International dental journal · 2022Review
- Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe objectives of this study were to compare the amount of fluoride delivered via a topical application of 38% silver diamine fluoride (SDF) solution and 5% sodium fluoride (NaF) varnish as well as to determine the amount of 38% SDF solution delivered using various micro-applicators.
methodsThe weights of 38% SDF (Saforide) and 5% NaF (Duraphat) applied to the occlusal surface of an extracted human upper first premolar with a regular-size (2.50-mm tip diameter) micro-applicator were measured using an electronic-analytical balance. Afterwards, the weight of 38% SDF applied to a premolar using the micro-applicators of 5 common brands (Premium Plus, 3M, Dentsply, Elevate Oral Care, and SDI) were studied. The tip diameter of each micro-applicator was measured under a microscope. The weights of the delivered fluoride and silver were also calculated.
resultsThe mean weights of the fluoride delivered via the SDF solution and NaF varnish were 0.25 ± 0.07 mg and 0.49 ± 0.08 mg, respectively (P < .001). In addition, the tip diameters of the micro-applicators ranged from 1.89 ± 0.03 mm to 2.76 ± 0.02 mm. The mean weights of the fluoride delivered per application of 38% SDF using different applicators ranged from 0.13 ± 0.06 mg to 0.30 ± 0.09 mg, whereas the mean weights of the silver ranged from 0.76 ± 0.32 mg to 1.68 ± 0.50 mg. The weights of the delivered 38% SDF solution varied with the brand and with the tip diameters of the dental micro-applicators (P < .001).
conclusionsThe fluoride of the 38% SDF solution delivered topically was significantly less than that of 5% NaF varnish. Moreover, the amount of SDF solution delivered depends on the brand and size of the micro-applicators.
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