Evidence map›Paper›PMID 35569989›Full record

ArticleInternal medicine (Tokyo, Japan)2022

Bing-Neel Syndrome Successfully Treated with Tirabrutinib.

Takashi Oyama, Kazuki Taoka, Akira Chiba, Kensuke Matsuda, Hiroaki Maki, Yosuke Masamoto, Mineo Kurokawa

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Takashi OyamaDepartment of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, Japan.
Kazuki TaokaDepartment of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, Japan.
Akira ChibaDepartment of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, Japan.
Kensuke MatsudaDepartment of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, Japan.
Hiroaki MakiDepartment of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, Japan.
Yosuke MasamotoDepartment of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, Japan.
Mineo KurokawaDepartment of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, Japan.
The University of Tokyo · JPUniversity of Tokyo Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bing-Neel syndrome (BNS) is a rare central nervous system manifestation of lymphoplasmacytic lymphoma/Waldenström macroglobulinemia (LPL/WM). We herein report a 62-year-old man with LPL/WM after multiple chemotherapies. He had weakness of lower extremities and elevated serum IgM levels. A bone marrow examination showed lymphoplasmacytic cells infiltration. Contrast-enhanced magnetic resonance imaging suggested enhancing lesions in the cauda equina roots. He was diagnosed with BNS and started on treatment with tirabrutinib 480 mg daily. Within three months, he showed clinical and radiologic improvement. Tirabrutinib may have utility as an effective treatment for BNS.

Indexed as

Brain DiseasesNeurodegenerative DiseasesWaldenstrom MacroglobulinemiaHumansImidazolesMaleMiddle AgedPyrimidinesSyndromeImidazolesPyrimidinestirabrutinibBing-Neel syndromeibrutiniblymphoplasmacytic lymphomatirabrutinibWaldenström macroglobulinemia

Identifiers

PMID35569989
PMCPMC9790791
OpenAlexW4280615741

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.