Evidence map›Paper›PMID 35569336›Full record

ArticleComputers in biology and medicine2022

Decoding clinical biomarker space of COVID-19: Exploring matrix factorization-based feature selection methods.

Farshad Saberi-Movahed, Mahyar Mohammadifard, Adel Mehrpooya, Mohammad Rezaei-Ravari, Kamal Berahmand, Mehrdad Rostami, Saeed Karami, Mohammad Najafzadeh, Davood Hajinezhad, Mina Jamshidi and 12 more

Abstract read
In one paragraph

Article in Computers in biology and medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  5. Review
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  9. Article
  10. A Review of Virus-Like Particle-Based SARS-CoV-2 Vaccines in Clinical Trial Phases.Iranian journal of pharmaceutical research : IJPR · 2022
    Review
  11. Article
  12. Review
  13. Socioeconomic impact due to COVID-19: An empirical assessment.Information processing & management · 2022
    Article
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  16. Article
  17. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors.

Farshad Saberi-MovahedCollege of Engineering, North Carolina State University, Raleigh, NC, 22606, USA.
Mahyar MohammadifardDepartment of Radiology, Birjand University of Medical Sciences, Birjand, Iran.
Adel MehrpooyaSchool of Mathematical Sciences, Science and Engineering Faculty, Queensland University of Technology (QUT), Brisbane, Australia.
Mohammad Rezaei-RavariDepartment of Computer Engineering, Shahid Bahonar University of Kerman, Kerman, Iran.
Kamal BerahmandSchool of Computer Science, Faculty of Science, Queensland University of Technology (QUT), Brisbane, Australia.
Mehrdad RostamiCenter for Machine Vision and Signal Analysis (CMVS), University of Oulu, Oulu, Finland.
Saeed KaramiDepartment of Mathematics, Institute for Advanced Studies in Basic Sciences (IASBS), Zanjan, 45137-66731, Iran.
Mohammad NajafzadehDepartment of Applied Mathematics, Faculty of Sciences and Modern Technologies, Graduate University of Advanced Technology, Kerman, Iran.
Davood HajinezhadSAS Institute Inc., Cary, NC, USA.
Mina JamshidiDepartment of Applied Mathematics, Faculty of Sciences and Modern Technologies, Graduate University of Advanced Technology, Kerman, Iran.
Farshid AbediInfectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Mahtab MohammadifardDepartment of Pathology, Birjand University of Medical Sciences, Birjand, Iran.
Elnaz FarbodBaruch College, City University of New York, New York, USA.
Farinaz SafaviNeuroimmunology and Neurovirology Branch, National Institute of Neurological Disorders and Stroke, National Institute of Health, Bethesda, MD, USA.
Mohammadreza DorvashBiomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Viewbank, VIC, Australia.
Negar Mottaghi-DastjerdiDepartment of Pharmacognosy and Pharmaceutical Biotechnology, School of Pharmacy, Iran University of Medical Sciences, Tehran, Iran.
Shahrzad VahediIndependent Researcher, Vancouver, Canada.
Mahdi EftekhariDepartment of Computer Engineering, Shahid Bahonar University of Kerman, Kerman, Iran.
Farid Saberi-MovahedDepartment of Applied Mathematics, Faculty of Sciences and Modern Technologies, Graduate University of Advanced Technology, Kerman, Iran. Electronic address: fdsaberi@gmail.com.
Hamid Alinejad-RoknyBioMedical Machine Learning Lab, The Graduate School of Biomedical Engineering, UNSW Sydney, Sydney, NSW, 2052, Australia.
Shahab S BandFuture Technology Research Center, College of Future, National Yunlin University of Science and Technology, 123 University Road, Section 3, Douliou, Yunlin, 64002, Taiwan.
Iman TavassolyDepartment of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY10029, USA. Electronic address: tavassoly@gmail.com.

Funding

KITP Interdisciplinary Biology InitiativeR25GM067110 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI SHRAIMAN, BORIS I · 2003 to 2018
$1.8M
NIGMS NIH HHS R25 GM067110
6 · The paper itself

Abstract

One of the most critical challenges in managing complex diseases like COVID-19 is to establish an intelligent triage system that can optimize the clinical decision-making at the time of a global pandemic. The clinical presentation and patients' characteristics are usually utilized to identify those patients who need more critical care. However, the clinical evidence shows an unmet need to determine more accurate and optimal clinical biomarkers to triage patients under a condition like the COVID-19 crisis. Here we have presented a machine learning approach to find a group of clinical indicators from the blood tests of a set of COVID-19 patients that are predictive of poor prognosis and morbidity. Our approach consists of two interconnected schemes: Feature Selection and Prognosis Classification. The former is based on different Matrix Factorization (MF)-based methods, and the latter is performed using Random Forest algorithm. Our model reveals that Arterial Blood Gas (ABG) O

Indexed as

COVID-19BiomarkersHumansMachine LearningPandemicsTriageBiomarkersClinical biomarkerCOVID-19Dimensionality reductionFeature selectionMatrix factorization

Identifiers

PMID35569336
PMCPMC8979841

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.