Evidence map›Paper›PMID 35568989›Full record

ArticleEquine veterinary journal2022

Ultrasound biomicroscopy of the equine iridocorneal angle.

Kelly E Knickelbein, Mary E Lassaline, Soohyun Kim, Sara M Thomasy

Open access · greenAbstract read
In one paragraph

Article in Equine veterinary journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kelly E KnickelbeinVeterinary Medical Teaching Hospital, University of California-Davis, Davis, California, USA.ORCID https://orcid.org/0000-0002-8671-6661
Mary E LassalineDepartment of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, California, USA.ORCID https://orcid.org/0000-0003-4925-4522
Soohyun KimVeterinary Medical Teaching Hospital, University of California-Davis, Davis, California, USA.
Sara M ThomasyDepartment of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, California, USA.
University of California, Davis · USVeterinary Medical Teaching Hospital · US

Funding

VISION RESEARCH CORE GRANTP30EY012576 · NEI · UNIVERSITY OF CALIFORNIA DAVIS · PI LISA M OAKES · 1999 to 2026
$18.9M
ACVO Vision for Animals Foundation VAF2019-2NEI NIH HHS P30 EY012576NIH HHS P30 EY12576School of Veterinary Medicine, University of California, Davis RM Cello Endowment
6 · The paper itself

Abstract

backgroundThe iridocorneal angle (ICA) is the major pathway of aqueous humour outflow from the anterior chamber of the eye. Ultrasound biomicroscopy (UBM) has been utilised to characterise the morphology of this drainage pathway in numerous species. UBM may allow for early recognition of aqueous humour outflow obstructions in horses, allowing for earlier recognition of risk for glaucoma, a vision-threatening and painful disease. UBM morphology of the normal equine ICA has yet to be described.

objectivesTo determine the ultrasonographic morphology of the equine ICA by UBM in standing sedated horses. STUDY

designIn vivo experimental study.

methodsThirty healthy adult horses underwent UBM of the ICA at four locations (superior, temporal, inferior, nasal) of each eye utilising standing sedation, topical anaesthesia and auriculopalpebral perineural anaesthesia. Anatomic structures were defined on ultrasound images through comparison to published histologic photomicrographs of the equine ICA.

resultsUltrasound imaging of the ICA at all four locations was easily performed in standing, sedated horses. High-resolution images of the ICA allowed for identification of the pectinate ligament, corneoscleral trabecular meshwork (TM), uveal TM and supraciliary TM. MAIN LIMITATIONS: Pupil size was midrange in all eyes, but was not strictly controlled. Lighting conditions not controlled. Various breeds included.

conclusionIn vivo UBM of the equine ICA is feasible and provides high-resolution images of the structures of the aqueous humour outflow pathway.

Indexed as

Eye DiseasesHorse DiseasesAnimalsAnterior ChamberAqueous HumorHorsesMicroscopy, AcousticUltrasonographyaqueous humoureyeglaucomahorseUBM

Identifiers

PMID35568989
PMCPMC9547819
OpenAlexW4280492475

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.